CAS 18771-50-1: Tetrahydrouridine

Description: Tetrahydrouridine (THU) is a nucleoside analog that primarily functions as an inhibitor of the enzyme cytidine deaminase, which is involved in the metabolism of nucleosides. Its chemical structure features a pyrimidine ring with a tetrahydrofuran moiety, contributing to its unique properties. THU is known for its ability to enhance the bioavailability of certain nucleoside analogs by preventing their degradation, thus increasing their therapeutic efficacy. It is often studied in the context of antiviral and anticancer therapies, particularly in combination with other nucleoside analogs. THU is typically administered in a pharmaceutical form, and its solubility and stability are important factors in its application. Additionally, it has been investigated for its potential role in modulating immune responses and in various biochemical research applications. Safety and toxicity profiles are essential considerations in its use, and ongoing research continues to explore its full range of biological activities and therapeutic potential.

Formula: C₉H₁₆N₂O₆

InChI: InChI=1S/C9H16N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4-8,12-15H,1-3H2,(H,10,16)/t4-,5?,6-,7-,8-/m1/s1

InChI key: InChIKey=UCKYOOZPSJFJIZ-XVKVHKPRSA-N

SMILES: O=C1NC(O)CCN1C2OC(CO)C(O)C2O

Synonyms:

• 1-(β-<span class="text-smallcaps">D</span>-Ribofuranosyl)-4-hydroxytetrahydro-1(1H)-pyrimidinone
• 2(1H)-Pyrimidinone, tetrahydro-4-hydroxy-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• 2(1H)-pyrimidinone, tetrahydro-4-hydroxy-1-beta-D-ribofuranosyl-
• 3,4,5,6-Tetrahydrouridine
• 4-hydroxy-1-(beta-D-ribofuranosyl)tetrahydropyrimidin-2(1H)-one
• 4-hydroxy-1-pentofuranosyltetrahydropyrimidin-2(1H)-one
• 5,6-Dihydrouridine
• Brn 0752319
• Nsc 112907
• Nsc-112907-D
• U 23284
• Uridine, 3,4,5,6-tetrahydro-
• Tetrahydrouridine
• 2(1H)-Pyrimidinone, tetrahydro-4-hydroxy-1-β-D-ribofuranosyl-
• 1-(β-D-Ribofuranosyl)-4-hydroxytetrahydro-1(1H)-pyrimidinone

Tetrahydrouridine

CAS: 18771-50-1

• Formula: C₉H₁₆N₂O₆
• Purity: 80%
• Color and Shape: Solid
• Molecular weight: 248.2331

Tetrahydrouridine

CAS: 18771-50-1

• Formula: C₉H₁₆N₂O₆
• Molecular weight: 248.24

3,4,5,6-Tetrahydrouridine (>80%)

CAS: 18771-50-1

Stability Light Sensitive Applications 3,4,5,6-Tetrahydrouridine, is a derivative of Uridine (U829910). Tetrahydrouridine (THU), is a …

• Formula: C₉H₁₆N₂O₆
• Purity: >80%
• Color and Shape: Neat
• Molecular weight: 248.23

Tetrahydrouridine

CAS: 18771-50-1

Please enquire for more information about Tetrahydrouridine including the price, delivery time and more detailed …

• Formula: C₉H₁₆N₂O₆
• Purity: Min. 95%
• Color and Shape: White Off-White Powder
• Molecular weight: 248.23 g/mol

Tetrahydrouridine

CAS: 18771-50-1

Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator.

• Formula: C₉H₁₆N₂O₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 248.23