CAS 187870-78-6

Rimeporide

Description:

Rimeporide is a chemical compound classified as a selective inhibitor of the sodium-hydrogen exchanger (NHE) and is primarily studied for its potential therapeutic applications in cardiovascular and renal diseases. It is known for its ability to modulate electrolyte balance and fluid retention, making it of interest in the treatment of conditions such as hypertension and heart failure. The compound exhibits a specific mechanism of action by inhibiting the NHE, which plays a crucial role in regulating intracellular pH and sodium levels. Rimeporide is typically characterized by its molecular structure, which includes specific functional groups that contribute to its biological activity. Additionally, it has been evaluated for its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, which are essential for understanding its efficacy and safety profile in clinical settings. As with many pharmacological agents, ongoing research continues to explore its full therapeutic potential and any associated side effects.

Formula: C₁₁H₁₅N₃O₅S₂

InChI: InChI=1S/C11H15N3O5S2/c1-6-4-8(20(2,16)17)9(21(3,18)19)5-7(6)10(15)14-11(12)13/h4-5H,1-3H3,(H4,12,13,14,15)

InChI key: InChIKey=GROMEQPXDKRRIE-UHFFFAOYSA-N

SMILES: S(C)(=O)(=O)C1=C(S(C)(=O)=O)C=C(C)C(C(NC(=N)N)=O)=C1

Synonyms:

• Benzamide, N-(aminoiminomethyl)-2-methyl-4,5-bis(methylsulfonyl)-
• N-(Aminoiminomethyl)-2-methyl-4,5-bis(methylsulfonyl)benzamide
• N-(Aminoiminomethyl)-4,5-bis(methanesulfonyl)-2-methylbenzamide
• Rimeporide [INN]
• Unii-Qh6B4V5743
• Rimeporide
• EMD-87580 >=98% (HPLC)
• EMD-87580
• N-carbamimidoyl-2-methyl-4,5-bis(methylsulfonyl)benzamide
• N-(diaminomethylidene)-2-methyl-4,5-bis(methylsulfonyl)benzamide

Rimeporide

CAS: 187870-78-6

Rimeporide

Formula: C₁₁H₁₅N₃O₅S₂

Purity: ≥95%

Molecular weight: 333.38

Ref: 54-BUP04792

N-(Aminoiminomethyl)-2-methyl-4,5-bis(methylsulfonyl)benzamide

CAS: 187870-78-6

Formula: C₁₁H₁₅N₃O₅S₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 333.3839

Ref: IN-DA00BAYE

Rimeporide

CAS: 187870-78-6

Rimeporide (EMD-87580) (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.

Formula: C₁₁H₁₅N₃O₅S₂

Purity: 97.66%

Color and Shape: Solid

Molecular weight: 333.384

Ref: TM-T5319

Rimeporide

CAS: 187870-78-6

N-Carbamimidoyl-2-methyl-4,5-bis(methylsulfonyl)benzamide

Formula: C₁₁H₁₅N₃O₅S₂

Purity: 99%

Molecular weight: 333.38

Ref: IN-DG01068854