CAS 1879-72-7

(11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-21-(1-oxo-3-phenylpropoxy)pregna-1,4-diene-3,20-dione

Description:

The chemical substance known as "(11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-21-(1-oxo-3-phenylpropoxy)pregna-1,4-diene-3,20-dione," with the CAS number 1879-72-7, is a synthetic corticosteroid. It exhibits anti-inflammatory and immunosuppressive properties, making it useful in various therapeutic applications, particularly in treating conditions like asthma, allergies, and autoimmune disorders. The structure of this compound features a fluorine atom, hydroxyl groups, and a phenylpropoxy side chain, contributing to its biological activity and pharmacokinetics. The presence of the pregnane steroid backbone is characteristic of corticosteroids, which are derived from cholesterol. This compound's specific stereochemistry, indicated by the nomenclature, plays a crucial role in its interaction with glucocorticoid receptors, influencing its efficacy and potency. As with many corticosteroids, it may also have side effects, including potential impacts on metabolism and immune function, necessitating careful consideration in clinical use.

Formula: C₃₁H₃₇FO₆

InChI: InChI=1/C31H37FO6/c1-19-15-24-23-11-10-21-16-22(33)13-14-28(21,2)30(23,32)25(34)17-29(24,3)31(19,37)26(35)18-38-27(36)12-9-20-7-5-4-6-8-20/h4-8,13-14,16,19,23-25,34,37H,9-12,15,17-18H2,1-3H3/t19-,23+,24+,25+,28+,29+,30+,31+/m1/s1

InChI key: InChIKey=CTKMBLPPDDQOSU-JPYVRCQISA-N

SMILES: F[C@@]12[C@]([C@]3([C@@](C)([C@](C(COC(CCC4=CC=CC=C4)=O)=O)(O)[C@H](C)C3)C[C@@H]1O)[H])(CCC=5[C@]2(C)C=CC(=O)C5)[H]

Synonyms:

• (11Beta,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl 3-Phenylpropanoate
• Dexamethasone 21-hydrocinnamate
• Dexamethasone 21-phenylpropionate
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(1-oxo-3-phenylpropoxy)-, (11β,16α)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-hydrocinnamate
• Dexamethasone 21-(3-phenylpropionate)
• (11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-21-(1-oxo-3-phenylpropoxy)pregna-1,4-diene-3,20-dione
• Dexamethasone Phenylpropionate
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(1-oxo-3-phenylpropoxy)-, (11.beta.,16.alpha.)-
• [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 3-phenylpropanoate
• 9-Fluoro-11β,17-dihydroxy-16α-methyl-21-(1-oxo-3-phenylpropoxy)pregna-1,4-diene-3,20-dione

Dexamethasone Phenylpropionate

CAS: 1879-72-7

Formula: C₃₁H₃₇FO₆

Purity: 95%

Molecular weight: 524.6203

Ref: IN-DA002GK5

Dexamethasone Phenylpropionate

CAS: 1879-72-7

Formula: C₃₁H₃₇FO₆

Color and Shape: White To Off-White Solid

Molecular weight: 524.63

Ref: 4Z-D-3629

Dexamethasone Phenylpropionate

Controlled Product

CAS: 1879-72-7

Formula: C₃₁H₃₇FO₆

Color and Shape: Neat

Molecular weight: 524.62

Ref: TR-D222830

Dexamethasone Phenylpropionate

CAS: 1879-72-7

Formula: C₃₁H₃₇FO₆

Molecular weight: 524.63

Ref: ST-EA-CP-D17070

Dexamethasone 21-(3-phenylpropionate)

CAS: 1879-72-7

Dexamethasone 21-(3-phenylpropionate) is a corticosteroid that is used for the treatment of a variety of inflammatory skin conditions. Dexamethasone 21-(3-phenylpropionate) has been shown to be effective in the treatment of cutaneous lesions in mice and rabbits. This drug also has an anti-inflammatory effect, which may be due to its ability to inhibit cytokine production. Dexamethasone 21-(3-phenylpropionate) is not metabolized by liver enzymes and has a long half life, making it more predictable than prednisolone. This medication should not be used during pregnancy or if you are trying to become pregnant, as it may cause abortion or premature birth. It should also not be used by women who are breastfeeding, as it can pass through breast milk and affect the baby.

Formula: C₃₁H₃₇FO₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 524.62 g/mol

Ref: 3D-FD31959