CAS 18797-79-0

corynoline

Description:

Corynoline is a chemical compound classified as an alkaloid, primarily derived from various plant sources, particularly those in the family of Amaryllidaceae. It is known for its structural complexity, featuring a bicyclic framework that contributes to its biological activity. Corynoline exhibits a range of pharmacological properties, including potential anti-inflammatory and analgesic effects, which have garnered interest in medicinal chemistry. The compound's mechanism of action is often linked to its interaction with neurotransmitter systems, although specific pathways may vary. In terms of physical properties, corynoline is typically characterized by its solubility in organic solvents and limited solubility in water, which is common for many alkaloids. Its stability can be influenced by environmental factors such as pH and temperature. Research into corynoline continues to explore its therapeutic potential, alongside investigations into its biosynthesis and ecological roles within its native plant species. As with many natural products, further studies are necessary to fully elucidate its mechanisms and applications in medicine.

Formula: C₂₁H₂₁NO₅

InChI: InChI=1/C21H21NO5/c1-21-14-3-4-15-19(27-10-24-15)13(14)8-22(2)20(21)12-7-17-16(25-9-26-17)5-11(12)6-18(21)23/h3-5,7,18,20,23H,6,8-10H2,1-2H3/t18-,20+,21-/m0/s1

InChI key: InChIKey=IQUGPRHKZNCHGC-TYPHKJRUSA-N

SMILES: C[C@@]12[C@@](C=3C(C[C@@H]1O)=CC4=C(C3)OCO4)(N(C)CC=5C2=CC=C6C5OCO6)[H]

Synonyms:

• (5bR,6S,12bR)-5b,6,7,12b,13,14-Hexahydro-5b,13-dimethyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol
• 13-Methylchelidonine
• Chelidonine, 13-methyl-
• [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol, 5b,6,7,12b,13,14-hexahydro-5b,13-dimethyl-, (5bR,6S,12bR)-
• [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol, 5b,6,7,12b,13,14-hexahydro-5b,13-dimethyl-, [5bR-(5bα,6β,12bα)]-
• [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-5b,13-
• [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine, chelidonine deriv.
• dimethyl-, (5bR,6S,12bR)-
• (+)-corynoline
• Corynoline
• (5bR)-5bα,13-Dimethyl-5bα,6,7,12bα,13,14-hexahydro[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine-6β-ol
• 13-Methylchelidonan-11β-ol
• CORYNOLINE(P)

Corynoline

CAS: 18797-79-0

Corynoline

Purity: ≥98%

Molecular weight: 367.4g/mol

Ref: 54-BUP10563

Corynoline

CAS: 18797-79-0

Formula: C₂₁H₂₁NO₅

Molecular weight: 367.40

Ref: 7W-GY0250

Corynoline

CAS: 18797-79-0

Corynoline is a reversible and noncompetitive inhibitor of acetylcholinesterase(AChE) with the IC50 value of 30.6 microM, which exhibits the potent anti-inflammatory and/or immunosuppressive activity, the potent inhibitory activity of corynoline for the ICAM-1/LFA-1 adhesion and would be important on developing the clinically usable drugs for the inflammatory diseases.

Formula: C₂₁H₂₁NO₅

Purity: 95%~99%

Molecular weight: 367.401

Ref: BP-BP0398

Corynoline

CAS: 18797-79-0

1. Corynoline ((+)-Corynoline) is an acetylcholinesterase inhibitor.

Formula: C₂₁H₂₁NO₅

Purity: 98.17% - 99.29%

Color and Shape: Solid

Molecular weight: 367.40

Ref: TM-T6S2356

Corynoline

CAS: 18797-79-0

Natural alkaloid

Formula: C₂₁H₂₁NO₅

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 367.4

Ref: 5G-80574

Corynoline

Controlled Product

CAS: 18797-79-0

Formula: C₂₁H₂₁NO₅

Color and Shape: Yellow

Molecular weight: 367.40

Ref: TR-C696900

CORYNOLINE

CAS: 18797-79-0

Molecular weight: 367.401001

Ref: 10-F859711

Corynoline

CAS: 18797-79-0

Corynoline is an isoquinoline alkaloid, which is derived from the plant genus Corydalis, specifically Corydalis bungeana Turcz. It exhibits its mode of action primarily through modulating various cellular pathways, including the inhibition of acetylcholinesterase and interference with certain receptor-mediated signaling processes. This biochemical activity underpins its potential pharmacological uses.

Purity: Min. 95%

Ref: 3D-FC73889