CAS 188119-47-3

Orphanin FQ 2 (mouse)(9CI)

Description:

Orphanin FQ, also known as nociceptin, is a neuropeptide that plays a significant role in various physiological processes, including pain modulation, stress response, and regulation of mood. The specific variant "Orphanin FQ 2 (mouse)(9CI)" refers to a form of this peptide derived from mouse models, which is often used in research to study its effects in the central nervous system. The CAS number 188119-47-3 identifies this particular chemical substance uniquely. Orphanin FQ interacts with the nociceptin receptor (NOP), which is part of the opioid receptor family, but it does not exhibit the same analgesic properties as traditional opioids. Instead, it can have both pro-nociceptive and anti-nociceptive effects depending on the context and concentration. This peptide is also implicated in various behaviors, including anxiety and addiction, making it a subject of interest in pharmacological and neuroscientific studies. Its characteristics include being a small peptide with a specific amino acid sequence that determines its biological activity and receptor interactions.

Formula: C₉₂H₁₄₁N₂₃O₂₈S₂

Synonyms:

• Orphanin FQ 2
• 109: PN:US20090104234 SEQID: 109 unclaimed protein
• L-Glutamine,L-phenylalanyl-L-seryl-L-a-glutamyl-L-phenylalanyl-L-methionyl-L-arginyl-L-glutaminyl-L-tyrosyl-L-leucyl-L-valyl-L-leucyl-L-seryl-L-methionyl-L-glutaminyl-L-seryl-L-seryl-
• 59: PN: WO2008008805 SEQID: 60 unclaimed protein
• 62: PN:WO2007106799 SEQID: 160 unclaimed sequence
• 161: PN: US20090048431 SEQID: 160 claimedsequence
• NOCII

NocII

CAS: 188119-47-3

Orphan neuropeptide,stimulates locomotion in mice

Formula: C₉₂H₁₄₁N₂₃O₂₈S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 2081.37

Ref: TM-TP2275

NocII

CAS: 188119-47-3

NocII is a protein that is encoded by the NOC2 gene. It has been shown to have locomotor activity, which is linked to its ability to inhibit oxidation of dopamine in the brain. This inhibition of oxidation may be due to its ability to form conjugates with dopamine receptors and other proteins. NocII has also been shown to have antiviral properties, as it has been shown to reactivate latent virus infections in mice. This protein may also play a role in autoimmune diseases and cancer, as it is expressed at high levels in human populations with these conditions. The knockout of this gene results in mice that are susceptible to dopamine-induced locomotion and plate test-induced seizures.

Formula: C₉₂H₁₄₁N₂₃O₂₈S₂

Purity: Min. 95%

Molecular weight: 2,081.4 g/mol

Ref: 3D-NHA11947