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CAS 188240-32-6

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4-Oxo-Valsartan Benzyl Ester

Description:
4-Oxo-Valsartan Benzyl Ester is a chemical compound that belongs to the class of angiotensin II receptor antagonists, which are primarily used in the treatment of hypertension and heart failure. This compound is a derivative of Valsartan, featuring a benzyl ester modification that enhances its pharmacological properties. It typically exhibits a white to off-white crystalline appearance and is soluble in organic solvents, while having limited solubility in water. The molecular structure includes a carboxylic acid group, which is esterified with a benzyl group, contributing to its lipophilicity and potential bioavailability. The compound's mechanism of action involves blocking the effects of angiotensin II, leading to vasodilation and reduced blood pressure. Additionally, it may possess antioxidant properties, which can be beneficial in cardiovascular health. As with many pharmaceutical compounds, safety and efficacy are evaluated through rigorous clinical trials, and it is essential to consider potential side effects and interactions with other medications. Proper handling and storage conditions are also crucial to maintain the compound's stability and effectiveness.
Formula:C31H33N5O4
Synonyms:
  • N-(1,4-Dioxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Phenylmethyl Ester
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