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CAS 1883545-47-8

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I-BET 151 hydrochloride

Description:
I-BET 151 hydrochloride is a small molecule inhibitor primarily known for its role in targeting the bromodomain and extraterminal (BET) family of proteins, which are involved in the regulation of gene expression. This compound is characterized by its ability to disrupt the interaction between BET proteins and acetylated lysines on histones, thereby influencing transcriptional processes associated with various diseases, including cancer and inflammatory conditions. I-BET 151 hydrochloride is typically presented as a white to off-white solid and is soluble in organic solvents, making it suitable for in vitro and in vivo studies. Its pharmacological profile suggests potential therapeutic applications, particularly in oncology, where it may help in the modulation of oncogene expression. As with many chemical substances, handling I-BET 151 hydrochloride requires adherence to safety protocols, including the use of personal protective equipment, due to its bioactive nature. Research continues to explore its efficacy and mechanisms of action in various biological contexts.
Formula:C23H22ClN5O3
Synonyms:
  • I-BET 151 hydrochloride
  • I-BET 151 dihydrochloride
  • 7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydroxy-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one dihydrochloride
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