
CAS 1884227-58-0
:Belinostat Z-isomer
Description:
Belinostat Z-isomer, identified by the CAS number 1884227-58-0, is a chemical compound that belongs to the class of hydroxamic acid derivatives. It is primarily recognized for its role as a histone deacetylase (HDAC) inhibitor, which is significant in the context of cancer therapy, as it can influence gene expression and promote apoptosis in cancer cells. The Z-isomer specifically refers to the geometric configuration of the compound, which can affect its biological activity and interaction with target proteins. Belinostat is characterized by its ability to modulate various cellular processes, including cell cycle regulation and differentiation. The compound is typically administered in a clinical setting for the treatment of hematological malignancies, such as peripheral T-cell lymphoma. Its pharmacological profile includes a favorable absorption and distribution in the body, although potential side effects may include gastrointestinal disturbances and hematological toxicity. Overall, Belinostat Z-isomer represents a promising therapeutic agent in oncology, with ongoing research aimed at optimizing its efficacy and safety.
Formula:C15H14N2O4S
Synonyms:- Belinostat Impurity 9
- Belinostat Z-isomer
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