CAS 1885-14-9

Phenyl chloroformate

Description:

Phenyl chloroformate, with the CAS number 1885-14-9, is an organic compound characterized by its structure, which includes a phenyl group attached to a chloroformate functional group. It appears as a colorless to pale yellow liquid with a distinctive odor. This compound is known for its reactivity, particularly as an acylating agent in organic synthesis, where it is often used to introduce the phenyl carbamate moiety into various substrates. Phenyl chloroformate is soluble in organic solvents such as dichloromethane and ether but is less soluble in water. It is sensitive to moisture and can hydrolyze in the presence of water, releasing hydrochloric acid and forming phenol and carbon dioxide. Due to its reactivity, it should be handled with care, as it can cause irritation to the skin, eyes, and respiratory system. Proper safety precautions, including the use of personal protective equipment, are essential when working with this compound in a laboratory setting.

Formula: C₇H₅ClO₂

InChI: InChI=1S/C7H5ClO2/c8-7(9)10-6-4-2-1-3-5-6/h1-5H

InChI key: InChIKey=AHWALFGBDFAJAI-UHFFFAOYSA-N

SMILES: O(C(Cl)=O)C1=CC=CC=C1

Synonyms:

• Chlorameisensaeure-Phenylester
• Chlorocarbonic acid phenyl ester
• Chloroformate, Phenyl
• Chloroformiate de phenyle
• Chloroformic acid phenyl ester
• Cloroformiato De Fenilo
• Formic acid, chloro-, phenyl ester
• Nsc 210946
• Phenyl Chloroformate
• Phenyl carbonochloridate
• Phenyl chlorocarbonate
• Phenylchlorformiat
• Phenylchloroformic acid
• Phenyloxycarbonyl chloride

Phenyl Chloroformate

CAS: 1885-14-9

Formula: C₇H₅ClO₂

Purity: >98.0%(GC)(T)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 156.57

Ref: 3B-C0649

Phenyl chloroformate, 99%

CAS: 1885-14-9

Phenyl chloroformate is used in the synthesis of poly(2-(phenoxycarbonyloxy)ethyl methacrylate) and phenyl-(4-vinylphenyl) carbonate. It acts as a precursor of phenyl mixed anhydrides which are used in peptide coupling reactions. It serves as a dehydrating reagent for the conversion of primary amide

Formula: C₇H₅ClO₂

Purity: 99%

Color and Shape: Clear colorless, Liquid

Molecular weight: 156.57

Ref: 02-A12618

Phenyl Chloroformate

CAS: 1885-14-9

Formula: C₇H₅ClO₂

Color and Shape: Colorless Oil

Molecular weight: 156.57

Ref: 4Z-C-334004

Phenyl Chloroformate

Controlled Product

CAS: 1885-14-9

Applications Phenyl chloroformate is a corrosive liquid that is used to synthesize Urazole, a five membered heterocyclic compound that reacts with aldoses to form α and β pyranosides and furanosides. Phenyl chloroformate is also used as a reagent to prepare Sorafenib (S676850), a multikinase inhibitor that targets the tumour and tumour vasculature in patients with melanoma.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Boettecher, B. & Meister, A.: Anal. Biochem., 138, 449 (1984); Chai, W., et al.: Tetrahedron Lett., 53, 3514 (20112); Eisen, T., et al.: Brit. J. Cancer, 95, 581 (2006); Kolb, V., et al.: J. Mol. Evol., 38, 549 (1994); Llovet, J., et al.: Engl. J. Med., 359, 378 (2008)

Formula: C₇H₅ClO₂

Color and Shape: Neat

Molecular weight: 156.57

Ref: TR-P319880

Phenyl chloroformate

CAS: 1885-14-9

Phenyl chloroformate is a phenyl compound that is used as a reagent for cationic polymerization. This chemical reacts with amines to form an N-substituted amide in the presence of hydrogen chloride. The mechanism of this reaction is based on nucleophilic substitutions by the hydroxyl group of the phenyl group. Phenyl chloroformate has been used in the synthesis of fatty acids, which are important components of metabolic disorders such as diabetes mellitus type 2.

Formula: C₇H₅ClO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 156.57 g/mol

Ref: 3D-FP31271

Phenyl Chloroformate

CAS: 1885-14-9

Formula: C₇H₅ClO₂

Molecular weight: 156.6

Ref: ST-EA-CP-S16034