CAS 188612-53-5

5-Amino-1-(N-methylcarbamoyl)imidazole-4-carboxamide

Description:

5-Amino-1-(N-methylcarbamoyl)imidazole-4-carboxamide, with the CAS number 188612-53-5, is a chemical compound characterized by its imidazole ring structure, which is a five-membered aromatic ring containing two nitrogen atoms. This compound features an amino group and a carboxamide functional group, contributing to its polar nature and potential solubility in water. The presence of the N-methylcarbamoyl group enhances its reactivity and may influence its biological activity. Typically, compounds like this can be involved in various biochemical processes, potentially serving as intermediates in the synthesis of pharmaceuticals or as active ingredients in medicinal chemistry. Its structural features suggest it may participate in hydrogen bonding, which can affect its interactions with biological macromolecules. The compound's stability, reactivity, and solubility are influenced by its functional groups, making it of interest in both synthetic and medicinal chemistry contexts. Further studies would be necessary to fully elucidate its properties and potential applications.

5-Amino-N1-methyl-1H-imidazole-1,4-dicarboxamide

CAS: 188612-53-5

Formula: C₆H₉N₅O₂

Color and Shape: Solid

Molecular weight: 183.1680

Ref: IN-DA00ANFR

Temozolomide Impurity 4

CAS: 188612-53-5

Formula: C₆H₉N₅O₂

Color and Shape: Off-White Solid

Molecular weight: 184.17

Ref: 4Z-T-3410

5-Amino-N1-methyl-1H-Imidazole-1,4-dicarboxamide

Controlled Product

CAS: 188612-53-5

Formula: C₆H₉N₅O₂

Color and Shape: Neat

Molecular weight: 183.17

Ref: 86-MM1480.04

5-Amino-N1-methyl-1H-imidazole-1,4-dicarboxamide

Controlled Product

CAS: 188612-53-5

Applications 5-Amino-N1-methyl-1H-imidazole-1,4-dicarboxamide is a metabolite of Temozolomide (T017775); an imidazotetrazine alkylating agent and antineoplastic.
References Newlands, E.S., et al.: Cancer Treat. Rev., 23, 35 (1997); Kim, C., et al.: J. Biol. Chem., 274, 1233 (1999); Hait, W., et al.: Cancer Res., 69, 1263 (2009); Wang, Y., et al.: J. Org. Chem., 62, 7288 (1997)

Formula: C₆H₉N₅O₂

Color and Shape: Off-White

Molecular weight: 183.17

Ref: TR-A616300