CAS 1887237-54-8

6-Quinolinecarboxamide, 1-acetyl-4-[(5-chloro-2-pyrimidinyl)amino]-1,2,3,4-tetrahydro-2-methyl-, (2S,4R)-

Description:

6-Quinolinecarboxamide, 1-acetyl-4-[(5-chloro-2-pyrimidinyl)amino]-1,2,3,4-tetrahydro-2-methyl-, (2S,4R)- is a complex organic compound characterized by its unique structural features, which include a quinoline ring fused with a tetrahydro structure and a pyrimidine moiety. This compound exhibits a chiral center, indicated by its (2S,4R) configuration, which can influence its biological activity and interactions. The presence of the chloro substituent on the pyrimidine ring may enhance its pharmacological properties, potentially affecting its solubility and reactivity. As an amide, it possesses functional groups that can participate in hydrogen bonding, influencing its physical properties such as melting point and solubility in various solvents. The acetyl group contributes to its overall stability and may play a role in its biological activity. Compounds of this nature are often investigated for their potential therapeutic applications, particularly in medicinal chemistry, due to their ability to interact with biological targets.

Formula: C₁₇H₁₈ClN₅O₂

Synonyms:

• I-BET567
• 6-Quinolinecarboxamide, 1-acetyl-4-[(5-chloro-2-pyrimidinyl)amino]-1,2,3,4-tetrahydro-2-methyl-, (2S,4R)-

I-BET567

CAS: 1887237-54-8

I-BET567

Formula: C₁₇H₁₈ClN₅O₂

Purity: ≥98%

Molecular weight: 359.81

Ref: 54-BUP03147

I-BET567

CAS: 1887237-54-8

I-BET567: potent, oral pan-BET inhibitor; pIC50s: 6.9 (BRD4 BD1), 7.2 (BD2); effective in mouse cancer and inflammation models.

Formula: C₁₇H₁₈ClN₅O₂

Purity: 99.8%

Color and Shape: Solid

Molecular weight: 359.81

Ref: TM-T9619

I-BET567

CAS: 1887237-54-8

(2S,4R)-1-Acetyl-4-((5-chloropyrimidin-2-yl)amino)-2-methyl-1,2,3,4-tetrahydroquinoline-6-carboxamide

Formula: C₁₇H₁₈ClN₅O₂

Purity: 98%

Molecular weight: 359.81

Ref: IN-DG01437353