CAS 188791-09-5

N-[3,5-Dichloro-2-hydroxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoyl]-L-phenylalanine ethyl ester dihydrochloride

Description:

N-[3,5-Dichloro-2-hydroxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoyl]-L-phenylalanine ethyl ester dihydrochloride, with CAS number 188791-09-5, is a synthetic compound that belongs to the class of amino acid derivatives. This substance features a complex structure characterized by the presence of a dichlorophenol moiety, which contributes to its biological activity. The compound includes a piperazine ring, which is often associated with pharmacological properties, particularly in the development of drugs targeting the central nervous system. The ethyl ester functional group enhances its lipophilicity, potentially improving its absorption and bioavailability. As a dihydrochloride salt, it is likely to exhibit increased solubility in aqueous environments, which is advantageous for formulation in pharmaceutical applications. The compound's specific interactions and mechanisms of action would depend on its target biological pathways, making it of interest in medicinal chemistry and drug development. Overall, its unique structural features suggest potential utility in therapeutic contexts, although detailed studies would be necessary to elucidate its full profile.

Formula: C₂₅H₃₃Cl₄N₃O₅

Synonyms:

• Jte-607

JTE607Dihydrochloride

CAS: 188791-09-5

Formula: C₂₅H₃₃Cl₄N₃O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 597.3586

Ref: IN-DA01E3IA

(S)-Ethyl 2-(3,5-Dichloro-2-Hydroxy-4-(2-(4-Methylpiperazin-1-Yl)Ethoxy)Benzamido)-3-Phenylpropanoate Dihydrochloride

CAS: 188791-09-5

(S)-Ethyl 2-(3,5-Dichloro-2-Hydroxy-4-(2-(4-Methylpiperazin-1-Yl)Ethoxy)Benzamido)-3-Phenylpropanoate Dihydrochloride

Purity: 98%

Molecular weight: 597.36g/mol

Ref: 54-OR1023131

JTE-607

CAS: 188791-09-5

JTE-607

Purity: ≥95%

Molecular weight: 597.36g/mol

Ref: 54-BUP02765

JTE-607

CAS: 188791-09-5

JTE-607 is a cytokine production inhibitor. JTE-607 induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.

Formula: C₂₅H₃₃Cl₄N₃O₅

Purity: 97.88%

Color and Shape: Solid

Molecular weight: 597.36

Ref: TM-T27695

Jte 607 dihydrochloride

CAS: 188791-09-5

Jte 607 is a prodrug that is hydrolyzed in vivo to form the active drug, Jte 607 acid. This drug has shown cardioprotective effects in animal models by reducing the expression of proinflammatory cytokines and increasing the production of anti-inflammatory cytokines. It also inhibits tumor necrosis factor (TNF) and interleukin-1β (IL-1β), which are proinflammatory cytokines. The molecular mechanism of Jte 607 is not yet fully understood, but it may be due to its ability to induce apoptosis and inhibit DNA synthesis in tumor cells.

Formula: C₂₂H₂₉Cl₄N₃O₃

Purity: Min. 95%

Molecular weight: 525.3 g/mol

Ref: 3D-NHA79109