CAS 18883-66-4: Streptozotocin

Description: Streptozotocin is a naturally occurring compound that is primarily derived from the bacterium Streptomyces achromogenes. It is classified as a nitrosourea and is known for its selective toxicity to pancreatic beta cells, making it particularly relevant in the context of diabetes research and treatment. The chemical formula of streptozotocin is C₁₃H₂₃N₅O₇, and it has a molecular weight of approximately 265.3 g/mol. This compound is characterized by its ability to induce DNA damage, leading to cell death, which is why it is utilized in cancer therapy, particularly for pancreatic cancer. Streptozotocin is administered intravenously and is known to have a range of side effects, including nephrotoxicity and gastrointestinal disturbances. Its mechanism of action involves the alkylation of DNA, which disrupts cellular replication and function. Due to its specific targeting of insulin-producing cells, streptozotocin has also been used in experimental models to induce diabetes in laboratory animals, aiding in the study of diabetes and potential treatments.

Formula: C₈H₁₅N₃O₇

InChI: InChI=1S/C8H15N3O7/c1-11(10-18)8(17)9-4(2-12)6(15)7(16)5(14)3-13/h2,4-7,13-16H,3H2,1H3,(H,9,17)/t4-,5+,6+,7+/m0/s1

InChI key: InChIKey=AGRCPNMCOXLKFO-BDVNFPICSA-N

SMILES: O=NN(C(=O)NC(C=O)C(O)C(O)C(O)CO)C

Synonyms:

• (5xi)-2-deoxy-2-{[methyl(nitroso)carbamoyl]amino}-D-lyxo-hexopyranose
• 2-Deoxy-2-(((Methylnitrosoamino)Carbonyl)Amino)-D-Glucose
• 2-Deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-<span class="text-smallcaps">D</span>-glucose
• 2-Desoxy-2-(3-Methyl-3-Nitrosoureido)-D-Glucopyranose
• 2-deoxy-2-{[methyl(nitroso)carbamoyl]amino}-D-glucopyranose
• 2-deoxy-2-{[methyl(nitroso)carbamoyl]amino}-alpha-D-glucopyranose
• 2-deoxy-2-{[methyl(nitroso)carbamoyl]amino}-beta-D-glucopyranose
• <span class="text-smallcaps">D</span>-Glucose, 2-deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-
• D-Glucose, 2-deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-
• Estreptozocin
• Estreptozocina
• Glucopyranose, 2-deoxy-2-(3-methyl-3-nitrosoureido)
• Glucopyranose, 2-deoxy-2-(3-methyl-3-nitrosoureido)-, <span class="text-smallcaps">D</span>-
• Glucopyranose, 2-deoxy-2-(3-methyl-3-nitrosoureido)-, D-
• Nsc 37917
• Nsc 85998
• STZ
• Streptozocine
• Streptozoticin
• Streptozotocin
• Strz
• U 9889
• Zanosar

Streptozotocin, 97+%

CAS: 18883-66-4

Streptozotocin is used to induce Type 1 diabetes for medicine. This Thermo Scientific Chemicals brand …

• Formula: C₈H₁₅N₃O₇
• Purity: 97+%
• Color and Shape: White to pale yellow, Powder
• Molecular weight: 265.22

D-Glucose, 2-deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-

CAS: 18883-66-4

• Formula: C₈H₁₅N₃O₇
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 265.2206

Streptozocin

CAS: 18883-66-4

Streptozocin (NSC-85998) is an antibiotic that induces DNA methylation.

• Formula: C₈H₁₅N₃O₇
• Purity: 100% - 99.56%
• Color and Shape: Pale Yellow Crystalline Powder
• Molecular weight: 265.22

Streptozocin

CAS: 18883-66-4

• Purity: 99.9%
• Molecular weight: 265.22g/mol

Streptozotocin

CAS: 18883-66-4

• Formula: C₈H₁₅N₃O₇
• Purity: By hplc: 99.8% by area (Typical Value in Batch COA)
• Color and Shape: faint yellow solid
• Molecular weight: 265.22g/mol

Streptozocin

CAS: 18883-66-4

• Formula: C₈H₁₅N₃O₇
• Purity: ≥ 98.0%
• Color and Shape: White to light-yellow powder
• Molecular weight: 265.22

Streptozotocin

CAS: 18883-66-4

M02540 - Streptozotocin

• Formula: C₈H₁₅N₃O₇
• Purity: >95%
• Color and Shape: Solid
• Molecular weight: 265.22198486328125

Streptozotocin

CAS: 18883-66-4

Applications Streptozotocin is used in the treatment metastatic cancer of the pancreatic islet cells. Streptozotocin …

• Formula: C₈H₁₅N₃O₇
• Color and Shape: Neat
• Molecular weight: 265.22

Streptozocin

CAS: 18883-66-4

A toxic glucosamine derivative, widely used for the induction of diabetes in experimental animals. The …

• Formula: C₈H₁₅N₃O₇
• Purity: Min. 98 Area-%
• Color and Shape: Off-White Powder
• Molecular weight: 265.2 g/mol

Streptozotocin (STZ) extrapure, 98%

CAS: 18883-66-4

• Formula: C₈H₁₅N₃O₇
• Purity: min. 98%
• Color and Shape: White to off-white to pale yellow, Crystalline powder
• Molecular weight: 265.22

Streptozotocin (STZ) for cell culture, 98%, Endotoxin (BET) 0.05EU/mg

CAS: 18883-66-4

• Formula: C₈H₁₅N₃O₇
• Purity: min. 98%
• Color and Shape: White to off-white to pale yellow, Crystalline powder
• Molecular weight: 265.22