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CAS 188970-92-5

:

Fmoc-Dap(Aloc)-OH

Description:
Fmoc-Dap(Aloc)-OH, also known as 9-fluorenylmethoxycarbonyl-2,3-diaminopropionic acid with an allyloxycarbonyl (Aloc) protecting group on the amino side chain, is a chemical compound commonly used in peptide synthesis and drug development. This substance features a fluorenylmethoxycarbonyl (Fmoc) group, which serves as a protective group for the amino functionality, allowing for selective reactions during peptide assembly. The presence of the Aloc group provides additional protection and can be selectively removed under specific conditions, facilitating the synthesis of complex peptides. Fmoc-Dap(Aloc)-OH is characterized by its stability under standard laboratory conditions, making it suitable for various synthetic applications. Its structure includes both amine and carboxylic acid functional groups, contributing to its reactivity in coupling reactions. The compound is typically used in solid-phase peptide synthesis, where it aids in the formation of peptide bonds while maintaining the integrity of the peptide chain during the synthesis process. Overall, Fmoc-Dap(Aloc)-OH is a valuable intermediate in the field of medicinal chemistry and peptide research.
Formula:C22H22N2O6
InChI:InChI=1/C22H22N2O6/c1-2-11-29-21(27)23-12-19(20(25)26)24-22(28)30-13-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h2-10,18-19H,1,11-13H2,(H,23,27)(H,24,28)(H,25,26)/t19-/m0/s1
SMILES:C=CCOC(=NC[C@@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12)O
Synonyms:
  • Fmoc-Dap(Alloc)-OH
  • Fmoc-Dap(Alloc)
  • N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-{[(prop-2-en-1-yloxy)carbonyl]amino}-L-alanine
  • N-BETA-ALLOC-N-ALPHA-FMOC-L-2,3-DIAMINOPROPIONIC ACID
  • N-α-Fmoc-N-β-Aloc-L-2,3-diaminopropionic acid
  • FMOC-DAP(ALOC)-OH USP/EP/BP
  • N-.ALPHA.-FMOC-N-.BETA.-ALLYLOXYCARBONYL-L-2,3-DIAMINOPROPIONIC ACID
  • FMOC-ALPHA,BETA-DIAMINOPROPIONIC ACID(ALOC)-OH
  • (S)-3-AllyloxycarbonylaMino-2-(FMoc-aMino)propionic acid, 95%
  • Fmoc-Dap(Alloc)-OH, ≥98.5% (HPLC)
  • See more synonyms
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