CAS 189035-22-1

6-BROMO-2,3-DIHYDRO-BENZOFURAN

Description:

6-Bromo-2,3-dihydro-benzofuran is an organic compound characterized by its fused benzene and furan rings, with a bromine substituent at the 6-position. This compound typically appears as a colorless to pale yellow liquid or solid, depending on its purity and form. It is known for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals due to its unique structural features that may interact with biological targets. The presence of the bromine atom can enhance the compound's reactivity and influence its biological activity. In terms of solubility, it is generally soluble in organic solvents, while its solubility in water is limited. The compound's stability can be affected by light and moisture, necessitating careful storage conditions. As with many brominated compounds, it may exhibit specific environmental and health considerations, making it essential to handle it with appropriate safety measures in laboratory settings. Overall, 6-bromo-2,3-dihydro-benzofuran is a compound of interest in both synthetic and applied chemistry.

Formula: C₈H₇BrO

InChI: InChI=1/C8H7BrO/c9-7-2-1-6-3-4-10-8(6)5-7/h1-2,5H,3-4H2

SMILES: c1cc(cc2c1CCO2)Br

Synonyms:

• 6-Bromo-2,3-Dihydro-1-Benzofuran

Benzofuran, 6-bromo-2,3-dihydro-

CAS: 189035-22-1

Formula: C₈H₇BrO

Purity: 97%

Color and Shape: Solid

Molecular weight: 199.0446

Ref: IN-DA002HR9

6-Bromo-2,3-dihydrobenzofuran

CAS: 189035-22-1

6-Bromo-2,3-dihydrobenzofuran

Purity: 97%

Molecular weight: 199.05g/mol

Ref: 54-OR74673

6-Bromo-2,3-dihydrobenzofuran

CAS: 189035-22-1

Formula: C₈H₇BrO

Purity: 97%

Color and Shape: Solid

Molecular weight: 199.047

Ref: 10-F241012

6-Bromo-2,3-dihydrobenzofuran

Controlled Product

CAS: 189035-22-1

Formula: C₈H₇BrO

Color and Shape: Neat

Molecular weight: 199.045

Ref: TR-B613580

6-Bromo-2,3-dihydrobenzofuran

CAS: 189035-22-1

6-Bromo-2,3-dihydrobenzofuran is an endothelin receptor antagonist that has been shown to have a high affinity for the endothelin receptor. It has been shown to inhibit the binding of endothelin to its receptors and therefore prevent the activation of the cells. 6-Bromo-2,3-dihydrobenzofuran is synthesized by reacting a Grignard reagent with 2,6-dichlorobenzonitrile in an intramolecular reaction. The resulting enolate is then reacted with aryllithium to form the bromide. The bromide can then be alkylated with chloromethyl methyl ether in an asymmetric synthesis, forming the desired product.

Formula: C₈H₇OBr

Purity: Min. 95%

Molecular weight: 199.04 g/mol

Ref: 3D-PHA03522