CAS 18905-73-2

Pentanamide, 2-amino-5-[(aminoiminomethyl)amino]-N-2-naphthalenyl-, monohydrochloride, (S)-

Description:

Pentanamide, 2-amino-5-[(aminoiminomethyl)amino]-N-2-naphthalenyl-, monohydrochloride, (S)-, is a complex organic compound characterized by its amide functional group and multiple amino groups, which contribute to its potential as a biological active agent. The presence of a naphthalene moiety suggests that it may exhibit aromatic properties, influencing its solubility and interaction with biological systems. As a hydrochloride salt, it is typically more soluble in water compared to its free base form, which is advantageous for pharmaceutical applications. The (S)- designation indicates that the compound has a specific stereochemistry, which can significantly affect its biological activity and interaction with receptors or enzymes. This compound may be of interest in medicinal chemistry, particularly in the development of drugs targeting specific biological pathways. Its structural complexity and functional groups suggest potential applications in areas such as cancer research or neuropharmacology, although specific biological activities would require further investigation through empirical studies.

Formula: C₁₆H₂₁N₅O·ClH

InChI: InChI=1S/C16H21N5O.ClH/c17-14(6-3-9-20-16(18)19)15(22)21-13-8-7-11-4-1-2-5-12(11)10-13;/h1-2,4-5,7-8,10,14H,3,6,9,17H2,(H,21,22)(H4,18,19,20);1H/t14-;/m0./s1

InChI key: InChIKey=WEVOXPYVEJEKIT-UQKRIMTDSA-N

SMILES: N(C([C@H](CCCNC(=N)N)N)=O)C1=CC2=C(C=C1)C=CC=C2.Cl

Synonyms:

• H-Arg-.beta.NA . HCl
• L-Arginine Beta-Naphthylamide Hydrochloride
• N5-(diaminomethylidene)-N-naphthalen-2-yl-L-ornithinamide hydrochloride
• N~5~-(diaminomethylidene)-N-naphthalen-2-yl-L-ornithinamide
• N~5~-(diaminomethylidene)-N-naphthalen-2-ylornithinamide hydrochloride
• Pentanamide, 2-amino-5-[(aminoiminomethyl)amino]-N-2-naphthalenyl-, monohydrochloride, (S)-
• Valeramide, 2-amino-5-guanidino-N-2-naphthyl-, monohydrochloride, <span class="text-smallcaps">L</span>-
• Valeramide, 2-amino-5-guanidino-N-2-naphthyl-, monohydrochloride, L-

H-Arg-βNA · HCl

CAS: 18905-73-2

Substrate for aminopeptidase B (arginine aminopeptidase) and cathepsin H.

Formula: C₁₆H₂₁N₅O·HCl

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 335.84

Ref: 01-4000556

L-Arginine β-naphthylamide HCl

CAS: 18905-73-2

Formula: C₁₆H₂₂ClN₅O

Molecular weight: 335.8318

Ref: IN-DA002HS0

L-Arginine β-naphthylamide hydrochloride

CAS: 18905-73-2

Formula: C₁₆H₂₁N₅O·HCl

Purity: ≥ 98%

Color and Shape: White to almost white powder

Molecular weight: 335.83

Ref: 7W-GM6678

L-Arginine β-naphthylamide hydrochloride

CAS: 18905-73-2

L-Arginine beta-naphthylamide hydrochloride (L-Arg) is a chemical compound that inhibits bacterial growth by binding to the enzyme arginase. This inhibition prevents the conversion of L-arginine to urea and ornithine, which are essential for bacterial growth. L-Arg has been shown to have an inhibitory effect on a mutant strain of Pseudomonas aeruginosa, which was resistant to ertapenem. The IC50 value of L-Arg was found to be 2.5 mM, with an EC50 value of 10 μM at 37°C in human liver cells. It has a pKa of 9.0 and an optimum pH of 7.2, making it more acidic than most other compounds in this class.

Formula: C₁₆H₂₁N₅O·HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 335.83 g/mol

Ref: 3D-FA52400

L-Arginine b-naphthylamide hydrochloride

CAS: 18905-73-2

Formula: C₁₆H₂₂ClN₅O

Purity: 99.0%

Molecular weight: 335.84

Ref: 10-F493704