CAS 189362-06-9

K 134

CAS: 189362-06-9

K 134 is a benzimidazole derivative that has been shown to be an effective inhibitor of muscle cell proliferation. K 134 inhibits the activity of fatty acid synthase and prevents the synthesis of eicosanoids, which are important mediators of inflammation. The inhibition of fatty acid synthase by K 134 may be due to its ability to bind to the active site and competitively inhibit the binding of acetyl-CoA. K 134 also has a dry weight-increasing effect on gastrocnemius muscle cells in rats, which is due to its ability to inhibit protein degradation as well as stimulate protein synthesis. K 134 has been shown to be effective against P. aeruginosa in a primary analysis and in vitro experiments, but it is not yet known whether this drug will be effective for humans.

Formula: C₂₂H₂₉N₃O₄

Purity: Min. 95%

Molecular weight: 399.5 g/mol

Ref: 3D-PHA36206

K134

CAS: 189362-06-9

K134 is an inhibitor of phosphodiesterase 3. The IC50s of K134 for PDE3A, PDE3B, PDE5, PDE2 and PDE4 are 0.1, 0.28, 12.1, >300 and >300 μM, respectively.

Formula: C₂₂H₂₉N₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 399.48

Ref: TM-T15640