CAS 18942-49-9
:N-tert-Butoxycarbonyl-D-phenylalanine
Description:
N-tert-Butoxycarbonyl-D-phenylalanine, commonly referred to as Boc-D-phenylalanine, is an amino acid derivative characterized by the presence of a tert-butoxycarbonyl (Boc) protecting group attached to the amino group of D-phenylalanine. This compound is typically used in peptide synthesis as a protective group that facilitates the selective modification of amino acids without interfering with other functional groups. It is a white to off-white solid that is soluble in organic solvents such as dichloromethane and dimethylformamide, but generally insoluble in water. The Boc group is known for its stability under basic conditions and can be easily removed under acidic conditions, making it a valuable tool in organic synthesis. The presence of the phenyl group contributes to the compound's hydrophobic characteristics, influencing its interactions in biological systems. As a chiral molecule, it exists in two enantiomeric forms, with the D-form being utilized in various biochemical applications. Overall, Boc-D-phenylalanine is significant in the field of medicinal chemistry and peptide research.
Formula:C14H19NO4
InChI:InChI=1S/C14H19NO4/c1-14(2,3)19-13(18)15-11(12(16)17)9-10-7-5-4-6-8-10/h4-8,11H,9H2,1-3H3,(H,15,18)(H,16,17)/t11-/m1/s1
InChI key:InChIKey=ZYJPUMXJBDHSIF-LLVKDONJSA-N
SMILES:[C@H](CC1=CC=CC=C1)(NC(OC(C)(C)C)=O)C(O)=O
Synonyms:- (2R)-2-(tert-Butoxycarbonylamino)-3-phenylpropanoic acid
- (2R)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoic acid
- (2R)-2-[(tert-Butoxycarbonyl)amino]-3-phenylpropionic acid
- (2R)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanoate
- (2R)-2-[[(tert-Butoxy)carbonyl]amino]-3-phenylpropanoic acid
- (R)-2-((tert-Butoxycarbonyl)amino)-3-phenylpropionic acid
- (R)-2-(tert-Butoxycarbonylamino)-3-phenylpropanoic acid
- (R)-N-(tert-Butoxycarbonyl)phenylalanine
- <span class="text-smallcaps">D</span>-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-
- Alanine, N-carboxy-3-phenyl-, N-tert-butyl ester, <span class="text-smallcaps">D</span>-
- BOC-<span class="text-smallcaps">D</span>-phenylalanine
- Boc-D-Phe-OH
- N-(tert-Butoxycarbonyl)-D-phenylalanine
- N-BOC-<span class="text-smallcaps">D</span>-phenylalanine
- N-Boc-D-phenylalanine
- N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">D</span>-phenylalanine
- N-tert-Butoxycarbonyl-<span class="text-smallcaps">D</span>-phenylalanine
- N-tert-Butyloxycarbonyl-<span class="text-smallcaps">D</span>-phenylalanine
- tert-Butoxycarbonyl-<span class="text-smallcaps">D</span>-phenylalanine
- tert-Butyloxycarbonyl-<span class="text-smallcaps">D</span>-phenylalanine
- tert-Butoxycarbonyl-D-phenylalanine
- Alanine, N-carboxy-3-phenyl-, N-tert-butyl ester, D-
- D-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-
- See more synonyms
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Found 13 products.
N-(tert-Butoxycarbonyl)-D-phenylalanine
CAS:Formula:C14H19NO4Purity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:265.31N-Boc-D-phenylalanine, 98%
CAS:<p>This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci</p>Formula:C14H19NO4Purity:98%Color and Shape:Crystals or powder or crystalline powder, WhiteMolecular weight:265.31Boc-D-Phe-OH
CAS:<p>Bachem ID: 4000781.</p>Formula:C14H19NO4Purity:> 99%Color and Shape:WhiteMolecular weight:265.31Boc-D-phenylalanine
CAS:<p>Boc-D-phenylalanine</p>Formula:C14H19NO4Purity:98%Color and Shape: white to off-white powderMolecular weight:265.30g/molBoc-D-Phe-OH
CAS:<p>Boc-D-Phe-OH is an antimicrobial peptide that is a small molecule with a molecular weight of 254.8. It has been shown to have anti-tumor activity, and can be used as an alternative to conventional chemotherapeutic drugs in the treatment of cancer. Boc-D-Phe-OH binds to the hydrophobic region on the surface of cells and disrupts the cell's membrane, causing cell death by apoptosis. This peptide also shows antibacterial activity against gramicidin S, which is a Gram-positive antibiotic that belongs to the polymyxins class. The antibacterial activity of this peptide may be due to its ability to bind to divalent cations such as calcium ions and magnesium ions. Boc-D-Phe-OH has been synthesized using a method that is both efficient and rapid (less than 12 hours). It has also been shown that this peptide does not show any</p>Formula:C14H19NO4Purity:Min. 95%Molecular weight:265.3 g/molBoc-D-Phe-OH
CAS:<p>M03311 - Boc-D-Phe-OH</p>Formula:C14H19NO4Purity:98%Color and Shape:Solid, Crystalline Powder or PowderMolecular weight:265.309N-Boc-D-phenylalanine
CAS:<p>D-Phenylalanine is a molecule that is used in the synthesis of peptidomimetics. It has been shown to have a high efficiency method in the synthesis of N-Boc-D-phenylalanine, which can be used as a glycosidic bond precursor. This chemical has been shown to have anti-tumor properties and it may be useful in binding experiments with ferrocene. The compound can also form hydrogen bonds with acids, such as the acid catalyst found in the digestive system.</p>Formula:C14H19NO4Purity:Min. 95%Color and Shape:PowderMolecular weight:265.31 g/molBOC-D-Phenylalanine extrapure, 99%
CAS:Formula:C14H19NO4Purity:min. 99%Color and Shape:White, PowderMolecular weight:265.30Boc-D-Phenylalanine
CAS:Controlled Product<p>Applications Boc-D-Phenylalanine is used in the synthesis of benzo[de][1,7]napthyridinones as PARP1 inhibitors. Also it is an important reagent in the preparation of proline-containing, β-turn mimetic cycle tetrapeptides.<br>References Ye, Na. et al.: J. Med. Chem., 56, 2885 (2013); Chouhan, G. et al.: Org. Lett., 15, 1206 (2013);<br></p>Formula:C14H19NO4Color and Shape:NeatMolecular weight:265.3
