
CAS 189638-30-0
:Afobazole dihydrochloride
Description:
Afobazole dihydrochloride is a synthetic compound primarily recognized for its anxiolytic properties, often used in the treatment of anxiety disorders. It is classified as a selective anxiolytic agent, which means it targets specific receptors in the brain to alleviate anxiety without the sedative effects commonly associated with traditional anxiolytics. The chemical structure of afobazole includes a benzodiazepine-like framework, although it does not belong to the benzodiazepine class. Its mechanism of action is thought to involve modulation of the GABAergic system, enhancing the effects of gamma-aminobutyric acid (GABA), a key neurotransmitter that promotes relaxation and reduces neuronal excitability. Afobazole dihydrochloride is typically administered orally and is well-absorbed in the gastrointestinal tract. It is known for having a favorable side effect profile, with minimal risk of dependence or withdrawal symptoms, making it a preferred choice for long-term management of anxiety. Additionally, it has been studied for its potential neuroprotective effects, contributing to its therapeutic appeal in various neurological conditions.
Formula:C15H21N3O2S·2ClH
InChI:InChI=1S/C15H21N3O2S.2ClH/c1-2-20-12-3-4-13-14(11-12)17-15(16-13)21-10-7-18-5-8-19-9-6-18;;/h3-4,11H,2,5-10H2,1H3,(H,16,17);2*1H
InChI key:InChIKey=OFMVMQZFMVQDFO-UHFFFAOYSA-N
SMILES:S(CCN1CCOCC1)C=2NC=3C(N2)=CC=C(OCC)C3.Cl
Synonyms:- 1H-Benzimidazole, 5-ethoxy-2-[[2-(4-morpholinyl)ethyl]thio]-, dihydrochloride
- Aphobazole dihydrochloride
- Afobazole dihydrochloride
- 1H-Benzimidazole, 6-ethoxy-2-[[2-(4-morpholinyl)ethyl]thio]-, hydrochloride (1:2)
- Afobazol dihydrochloride
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Found 2 products.
Fabomotizole dihydrochloride
CAS:<p>Fabomotizole (Afobazole, Obenoxazine, CM346) is a non-sedative anxiolytic with neuroprotective properties, launched in Russia 2000s; exact mechanism unclear.</p>Formula:C15H23Cl2N3O2SColor and Shape:SolidMolecular weight:380.33

