CAS 189681-71-8

Aplindore fumarate

Description:

Aplindore fumarate is a chemical compound primarily recognized for its role as a dopamine receptor agonist, specifically targeting the D2 receptor subtype. It is often studied in the context of neurological disorders, particularly for its potential therapeutic effects in conditions such as Parkinson's disease and other movement disorders. The substance exists as a fumarate salt, which enhances its solubility and stability. Aplindore fumarate is characterized by its ability to modulate dopaminergic activity, which is crucial for regulating motor control and various cognitive functions. In terms of its chemical structure, it features a complex arrangement that includes aromatic rings and functional groups conducive to receptor binding. The compound is typically administered in a controlled dosage form, and its pharmacokinetics involve absorption, distribution, metabolism, and excretion processes that are essential for its efficacy and safety profile. As with many pharmacological agents, understanding its mechanism of action and potential side effects is vital for its application in clinical settings.

Formula: C₁₈H₁₈N₂O₃·C₄H₄O₄

SMILES: C(NCC1=CC=CC=C1)[C@@H]2OC=3C4=C(C=CC3OC2)NC(=O)C4.C(=C/C(O)=O)\C(O)=O

Synonyms:

• 8H-1,4-Dioxino[2,3-e]indol-8-one, 2,3,7,9-tetrahydro-2-[[(phenylmethyl)amino]methyl]-, (2S)-, (2E)-2-butenedioate (1:1)
• WAY-DAB 452
• 8H-1,4-Dioxino[2,3-e]indol-8-one, 2,3,7,9-tetrahydro-2-[[(phenylmethyl)amino]methyl]-, (S)-, (E)-2-butenedioate (1:1)
• Aplindore fumarate

Aplindore Fumarate

CAS: 189681-71-8

Aplindore Fumarate

Purity: ≥98%

Molecular weight: 426.42g/mol

Ref: 54-BUP08413

Aplindore Fumarate

CAS: 189681-71-8

Aplindore Fumarate (DAB-452), a selective dopamine D2/D3 partial agonist, is used in Parkinson's and schizophrenia research.

Formula: C₂₂H₂₂N₂O₇

Purity: 99.66%

Color and Shape: Solid

Molecular weight: 426.42

Ref: TM-T30098