CAS 189689-94-9: ABT 491

Description: ABT-491, with the CAS number 189689-94-9, is a chemical compound that belongs to the class of small molecules known as selective inhibitors. It is primarily recognized for its role as a potent and selective antagonist of the protein kinase C (PKC) family, particularly targeting the PKC theta isoform. This compound has garnered interest in the field of medicinal chemistry due to its potential therapeutic applications, particularly in the treatment of autoimmune diseases and certain types of cancer. ABT-491 exhibits a favorable pharmacokinetic profile, which includes good oral bioavailability and the ability to penetrate biological membranes effectively. Its mechanism of action involves modulating immune responses, making it a candidate for further research in immunology. Additionally, ABT-491 has been studied for its effects on T-cell activation and proliferation, contributing to its potential utility in various clinical settings. As with many investigational compounds, ongoing studies are essential to fully elucidate its efficacy and safety profile in humans.

Formula: C₂₈H₂₃ClFN₅O₂

InChI: InChI=1/C28H22FN5O2.ClH/c1-5-18-7-6-8-25-26(18)21(16-34(25)28(36)32(3)4)27(35)19-9-10-20(22(29)13-19)15-33-17(2)31-23-14-30-12-11-24(23)33;/h1,6-14,16H,15H2,2-4H3;1H

Synonyms:

• A-137491, 4-Ethynyl-N,N-dimethyl-3-[3-fluoro-4-[(2-methyl-1H-imidazo-[4,5-c]pyridin-1-yl)methyl]benzoyl]-1H-indole-1-carboxamide hydrochloride
• 4-ethynyl-3-{3-fluoro-4-[(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)methyl]benzoyl}-N,N-dimethyl-1H-indole-1-carboxamide hydrochloride (1:1)

1H-Indole-1-carboxamide, 4-ethynyl-3-[3-fluoro-4-[(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)methyl]benzoyl]-N,N-dimethyl-, hydrochloride (1:1)

CAS: 189689-94-9

• Formula: C₂₈H₂₃ClFN₅O₂
• Molecular weight: 515.9659

ABT-491 hydrochloride

CAS: 189689-94-9

• Formula: C₂₈H₂₂N₅O₂F·HCl
• Molecular weight: 515.97

4-Ethynyl-3-[3-Fluoro-4-[(2-Methylimidazo[4,5-c]Pyridin-1-Yl)Methyl]Benzoyl]-N,N-Dimethylindole-1-Carboxamide Hydrochloride

CAS: 189689-94-9

Please enquire for more information about 4-Ethynyl-3-[3-Fluoro-4-[(2-Methylimidazo[4,5-c]Pyridin-1-Yl)Methyl]Benzoyl]-N,N-Dimethylindole-1-Carboxamide Hydrochloride including the price, delivery time and more …

• Formula: C₂₈H₂₃ClFN₅O₂
• Purity: Min. 95%
• Molecular weight: 515.97 g/mol

ABT 491 Hydrochloride

CAS: 189689-94-9

ABT-491 hydrochloride is an active platelet activator receptor (PAF-R) antagonist with good selectivity and oral …

• Formula: C₂₈H₂₃ClFN₅O₂
• Color and Shape: Solid
• Molecular weight: 515.97