CAS 189696-01-3

7-methoxycoumarin-4-acetyl-tyr-val-*ala-asp-ala-P

Description:

7-Methoxycoumarin-4-acetyl-tyr-val-*ala-asp-ala-P, identified by its CAS number 189696-01-3, is a synthetic compound that belongs to the class of coumarin derivatives. Coumarins are known for their diverse biological activities, including anti-inflammatory, antioxidant, and antimicrobial properties. This particular compound features a methoxycoumarin core, which is modified with an acetyl group and a peptide sequence that includes amino acids such as tyrosine (Tyr), valine (Val), alanine (Ala), and aspartic acid (Asp). The presence of these amino acids suggests potential applications in biochemistry and pharmacology, particularly in drug design and development. The structural modifications may enhance the compound's solubility, stability, and bioactivity. Additionally, compounds like this are often studied for their potential roles in cellular signaling and as fluorescent probes in biological research. Overall, 7-methoxycoumarin-4-acetyl-tyr-val-*ala-asp-ala-P exemplifies the intersection of organic chemistry and biochemistry, showcasing the potential for tailored compounds in therapeutic applications.

Formula: C₅₃H₆₄N₁₀O₁₉

Synonyms:

• Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH

Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH

CAS: 189696-01-3

Specific highly fluorescent FRET substrate for the determination of caspase-1 (ICE) and caspase-1-like enzyme activities. Cleavage of Mca-YVADAPK(Dnp) at the P1 Asp residue results in a continuous fluorescent assay monitored at an emission wavelength of 392 nm. Caspase-3 (apopain, CPP-32) is only weakly active on this substrate. Both caspase-1 and caspase-3 are involved in apoptosis. A specific substrate for renal ACE 2.

Formula: C₅₃H₆₄N₁₀O₁₉

Purity: > 96%

Color and Shape: Yellow

Molecular weight: 1145.15

Ref: 01-4030476

L-Lysine, N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-tyrosyl-L-valyl-L-alanyl-L-α-aspartyl-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)-

CAS: 189696-01-3

Formula: C₅₃H₆₄N₁₀O₁₉

Purity: 95%

Molecular weight: 1145.1309

Ref: IN-DA002DW9

Mca-YVADAP-Lys(Dnp)-OH

CAS: 189696-01-3

Mca-YVADAP-Lys(Dnp)-OH serves as a fluorescent substrate for caspase-1 and ACE2 to detect enzyme activity with ex/em=365/440 nm.

Formula: C₅₃H₆₄N₁₀O₁₉

Purity: 99.82%

Color and Shape: Solid

Molecular weight: 1145.13

Ref: TM-T76090

Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH trifluoroacetate

CAS: 189696-01-3

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Formula: C₅₃H₆₄N₁₀O₁₉•(C₂HF₃O₂)x

Purity: 95%Nmr

Color and Shape: Powder

Molecular weight: 1,145.13 g/mol

Ref: 3D-FM110927