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CAS 189807-20-3

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2,3,6-trifluorobenzoyl chloride

Description:
2,3,6-Trifluorobenzoyl chloride is an aromatic acyl chloride characterized by the presence of a benzene ring substituted with three fluorine atoms at the 2, 3, and 6 positions, along with a carbonyl chloride functional group. This compound is typically a colorless to pale yellow liquid and is known for its reactivity, particularly due to the presence of the acyl chloride functional group, which can readily participate in nucleophilic acyl substitution reactions. The trifluoromethyl groups enhance the electrophilicity of the carbonyl carbon, making it more susceptible to attack by nucleophiles. Additionally, the fluorine atoms contribute to the compound's unique physical and chemical properties, such as increased lipophilicity and altered boiling and melting points compared to non-fluorinated analogs. 2,3,6-Trifluorobenzoyl chloride is utilized in organic synthesis, particularly in the preparation of various fluorinated compounds and pharmaceuticals. However, it should be handled with care due to its corrosive nature and potential to release toxic gases upon hydrolysis.
Formula:C7H2ClF3O
InChI:InChI=1/C7H2ClF3O/c8-7(12)5-3(9)1-2-4(10)6(5)11/h1-2H
SMILES:c1cc(c(c(c1F)C(=O)Cl)F)F
Synonyms:
  • Trifluorobenzoylchloride
  • 2,3,6-Trifluorobenzoylchloride98%
  • Benzoyl chloride, 2,3,6-trifluoro-(9CI)
  • 2,3,6-Trifluorobenzoyl chloride 98%
  • 2,3,6-TRIFLUOROBENZOYL CHLORIDE
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