CAS 18982-54-2

2-Bromobenzyl alcohol

Description:

2-Bromobenzyl alcohol is an organic compound characterized by the presence of a bromine atom and a hydroxyl group (-OH) attached to a benzyl group. Its molecular formula is C7H8BrO, indicating that it contains seven carbon atoms, eight hydrogen atoms, one bromine atom, and one oxygen atom. This compound typically appears as a colorless to pale yellow liquid with a characteristic aromatic odor. It is soluble in organic solvents such as ethanol and ether but has limited solubility in water due to the hydrophobic nature of the benzyl group. 2-Bromobenzyl alcohol is often used as an intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and other fine chemicals. It can undergo various chemical reactions, including nucleophilic substitution and oxidation, making it a versatile building block in synthetic chemistry. Safety precautions should be taken when handling this compound, as it may pose health risks if inhaled or ingested, and appropriate personal protective equipment should be used.

Formula: C₇H₇BrO

InChI: InChI=1S/C7H7BrO/c8-7-4-2-1-3-6(7)5-9/h1-4,9H,5H2

InChI key: InChIKey=IOWGHQGLUMEZKG-UHFFFAOYSA-N

SMILES: C(O)C1=C(Br)C=CC=C1

Synonyms:

• (2-Bromophenyl)Methanol
• 1-Bromo-2-(hydroxymethyl)benzene
• 2-(Hydroxymethyl)phenyl bromide
• 2-Bromobenzenemethanol
• 2-Bromophenylmethanol
• 2-Hydroxymethyl-1-bromobenzene
• Benzenemethanol, 2-bromo-
• Benzyl alcohol, o-bromo-
• O-Bromobenzyl Alcohol
• 2-Bromobenzyl alcohol

2-Bromobenzyl Alcohol

CAS: 18982-54-2

Formula: C₇H₇BrO

Purity: >99.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 187.04

Ref: 3B-B1294

2-Bromobenzyl alcohol, 98%

CAS: 18982-54-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₇BrO

Purity: 98%

Color and Shape: White to cream, Crystals or powder or crystalline powder or fused solid

Molecular weight: 187.04

Ref: 02-A15700

Benzenemethanol, 2-bromo-

CAS: 18982-54-2

Formula: C₇H₇BrO

Purity: 98%

Color and Shape: Solid

Molecular weight: 187.0339

Ref: IN-DA002E0P

2-Bromobenzyl alcohol

CAS: 18982-54-2

2-Bromobenzyl alcohol

Formula: C₇H₇BrO

Purity: 98%

Color and Shape: white to off-white solid

Molecular weight: 187.03g/mol

Ref: 54-OR2107

2-Bromobenzyl alcohol

CAS: 18982-54-2

Formula: C₇H₇BrO

Molecular weight: 187.04

Ref: 7W-GK7874

2-Bromobenzyl alcohol

CAS: 18982-54-2

2-Bromobenzyl alcohol is an organic compound that contains a benzyl group, a hydroxyl group, and a bromine atom. It has been shown to be an effective catalyst for the cross-coupling of organic halides with alkyl Grignard reagents in the presence of sodium carbonate. The reaction mechanism involves formation of an intermolecular hydrogen bond between the carbonyl group and the 2-bromobenzyl alcohol. This reaction produces a constant that can be used to calculate the population growth rate.
2-Bromobenzyl Alcohol has optical properties that are similar to those of water, which makes it suitable for applications such as fuel cells or sensors.

Formula: C₇H₇BrO

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 187.03 g/mol

Ref: 3D-FB70569

2-Bromobenzyl alcohol

CAS: 18982-54-2

Formula: C₇H₇BrO

Purity: 98%

Color and Shape: Solid

Molecular weight: 187.036

Ref: 10-F008821

2-Bromobenzyl Alcohol

Controlled Product

CAS: 18982-54-2

Applications 2-Bromobenzyl Alcohol acts as a reagent for the synthesis of alkoxy tetrasubstituted chiral amino acids via three-component reaction of (diazo)oxindoles, alcohols and benzhydrylimino ester involving enantioselective trapping of oxonium ylides by benzhydrylimino ester. Also acts as a reagent for the preparation of orally active and liver-targeted prodrug of 5-fluoro-2'-deoxyuridine for treatment of hepatocellular carcinoma.
References Jia, S., et al.: Chin. Chem. Lett., PagesAhead of Print (2016); Peng, Y., et al.: J. Med. Chem., 59, 3661 (2016)

Formula: C₇H₇BrO

Color and Shape: Neat

Molecular weight: 187.03

Ref: TR-B679995