Description:m-Toluenesulphonyl chloride, also known as 3-toluenesulfonyl chloride, is an aromatic sulfonyl chloride with the chemical formula C7H7ClO2S. It is characterized by a toluene ring substituted with a sulfonyl chloride group at the meta position. This compound appears as a colorless to pale yellow liquid and is known for its strong odor. It is highly reactive, particularly with nucleophiles, making it a valuable reagent in organic synthesis, especially for the preparation of sulfonamides and other sulfonyl derivatives. m-Toluenesulphonyl chloride is soluble in organic solvents such as dichloromethane and ether but is not soluble in water. It is important to handle this compound with care, as it can cause severe irritation to the skin, eyes, and respiratory system. Proper safety precautions, including the use of personal protective equipment and working in a well-ventilated area or fume hood, are essential when working with this chemical.
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