CAS 18991-62-3

D-Glucose-6,6-D2

Description:

D-Glucose-6,6-D2 is a deuterated form of D-glucose, where the hydrogen atoms at the 6th carbon position are replaced with deuterium, a stable isotope of hydrogen. This modification allows for the use of D-Glucose-6,6-D2 in various scientific applications, particularly in nuclear magnetic resonance (NMR) spectroscopy and metabolic studies, as it provides insights into metabolic pathways and molecular interactions without altering the fundamental properties of glucose. D-Glucose itself is a simple sugar and an essential carbohydrate in biology, serving as a primary energy source for cells. The presence of deuterium can enhance the sensitivity and resolution of spectroscopic techniques. D-Glucose-6,6-D2 retains the characteristic properties of glucose, including its solubility in water and its role in cellular respiration and energy metabolism. Its molecular formula is C6H12O6, but with the deuterated positions, it is represented as C6D2H10O6. This compound is valuable in research fields such as biochemistry, pharmacology, and metabolic engineering.

Formula: C₆H₁₀D₂O₆

Synonyms:

• D-Glucose-6,6-d2 (pyrogen free)

D-Glucose-D2

CAS: 18991-62-3

D-Glucose-D2

Purity: 98%

Molecular weight: 182.17g/mol

Ref: 54-DE2032

D-Glucose-6,6-d2

CAS: 18991-62-3

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 182.17

Ref: 3U-D0900

D-Glucose-6,6-d2

Controlled Product

CAS: 18991-62-3

Applications Labelled D-Glucose is a simple sugar that is present in plants. A monosaccharide that may exist in open chain or cyclic conformation if in solution. It plays a vital role in photosynthesis and fuels the energy required for cellular respiration. D-Glucose is used in various metabolic processes including enzymic synthesis of cyclohexyl-α and β-D-glucosides. Can also be used as a diagnostic tool in detection of type 2 diabetes mellitus and potentially Huntington's disease through analysis of blood-glucose in type 1 diabetes mellitus.
References Wang, R., et al.: J. Mol. Catal. B. Enz., 56, 131 (2009); Springhorn, C. et al.: J. Clin. Endocrinol. Metab., 97, 4640 (2012); Hashimoto, K. et al.: J. Clin. Endocrinol. Metab., 97, 3016 (2012); Avelange, M. et al.: Plant. Phys., 94, 1157 (1990); Cramer, C. et al.: J. Chem. Soc., 115, 5745 (1993);

Formula: C₆₂H₂H₁₀O₆

Color and Shape: Neat

Molecular weight: 182.17

Ref: TR-G595003

D-[6,6'-2H2]Glucose

Controlled Product

CAS: 18991-62-3

D-[6,6'-2H2]Glucose is a carbohydrate that is present in many foods and also produced by the cells of the human body. It can be used as a biomarker for cancer cells because it is taken up by malignant cells at a higher rate than normal cells. D-[6,6'-2H2]Glucose is often used to assess the response of patients to chemotherapy treatment. The uptake of D-[6,6'-2H2]Glucose by malignant cells can be measured using vibrational spectroscopy or chromatographic science. The deformation of glucose molecules can be quantified using nuclear magnetic resonance (NMR) spectroscopy and this data can then be used to estimate the degree of glycolysis in specific tissues.

Formula: C₆D₂H₁₀O₆

Purity: Min. 95%

Molecular weight: 182.17 g/mol

Ref: 3D-MG74985

D-Glucose-6,6-C-d2

CAS: 18991-62-3

Formula: C₆H₁₀D₂O₆

Purity: %

Color and Shape: Solid

Molecular weight: 182.1682

Ref: IN-DA002E4F