CAS 189954-96-9

Firocoxib

Description:

Firocoxib is a selective non-steroidal anti-inflammatory drug (NSAID) primarily used in veterinary medicine, particularly for the treatment of pain and inflammation in dogs and horses. It belongs to the class of cyclooxygenase-2 (COX-2) inhibitors, which work by selectively inhibiting the COX-2 enzyme, thereby reducing the production of prostaglandins that mediate inflammation and pain. Firocoxib is characterized by its relatively high selectivity for COX-2 over COX-1, which helps minimize gastrointestinal side effects commonly associated with traditional NSAIDs. The compound is typically administered orally and is available in various formulations, including tablets and paste. Its pharmacokinetics indicate a moderate half-life, allowing for once-daily dosing in many cases. Firocoxib is generally well-tolerated, but like all medications, it may have potential side effects, including gastrointestinal upset, renal effects, and hypersensitivity reactions. As with any medication, it is essential to use Firocoxib under veterinary guidance to ensure safety and efficacy for the intended use.

Formula: C₁₇H₂₀O₅S

InChI: InChI=1S/C17H20O5S/c1-17(2)14(12-6-8-13(9-7-12)23(3,19)20)15(16(18)22-17)21-10-11-4-5-11/h6-9,11H,4-5,10H2,1-3H3

InChI key: InChIKey=FULAPETWGIGNMT-UHFFFAOYSA-N

SMILES: O(CC1CC1)C2=C(C(C)(C)OC2=O)C3=CC=C(S(C)(=O)=O)C=C3

Synonyms:

• 2(5H)-Furanone, 3-(cyclopropylmethoxy)-5,5-dimethyl-4-4-(methylsulfonyl)phenyl-
• 3-(Cyclopropyl-methoxy)-5,5-Dimethy l-4-(4-methylsulfonyl)phenyl)-5H-furan-2-one
• 3-(Cyclopropylmethoxy)-5,5-Dimethyl-4-(4-Methylsulfonylphenyl)Furan-2- One
• 3-(Cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone
• 3-(cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]furan-2(5H)-one
• Equioxx
• Equixx
• Librens
• Ml 1785713
• Previcox
• Firocoxib

2(5H)-Furanone, 3-(cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-

CAS: 189954-96-9

Formula: C₁₇H₂₀O₅S

Purity: 99%

Color and Shape: Solid

Molecular weight: 336.4027

Ref: IN-DA002E6F

Firocoxib

CAS: 189954-96-9

Formula: C₁₇H₂₀O₅S

Color and Shape: White To Off-White Solid

Molecular weight: 336.40

Ref: 4Z-F-081001

Firocoxib

CAS: 189954-96-9

Firocoxib

Purity: ≥98%

Molecular weight: 336.4g/mol

Ref: 54-BUP02461

Firocoxib

CAS: 189954-96-9

Formula: C₁₇H₂₀O₅S

Color and Shape: Neat

Molecular weight: 336.40

Ref: 04-C13646000

Firocoxib

CAS: 189954-96-9

Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.

Formula: C₁₇H₂₀O₅S

Purity: 99.84%

Color and Shape: Solid

Molecular weight: 336.4

Ref: TM-T7596

Firocoxib

CAS: 189954-96-9

Applications A selective cyclooxygenase-2-(COX-2) inhibitor. Anti-inflammatory; analgesic.
References McCann, M.E., et al.: Am. J. Vet. Res., 65, 503 (2004),

Formula: C₁₇H₂₀O₅S

Color and Shape: Off-White

Molecular weight: 336.40

Ref: TR-F356000

Firocoxib

CAS: 189954-96-9

COX-2 enzyme inhibitor; anti-inflammatory

Formula: C₁₇H₂₀O₅S

Purity: Min. 95%

Color and Shape: White To Off-White Solid

Molecular weight: 336.40 g/mol

Ref: 3D-FC23291

3-(Cyclopropylmethoxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one

CAS: 189954-96-9

Formula: C₁₇H₂₀O₅S

Purity: 99%

Molecular weight: 336.4

Ref: 10-F516398