CAS 189954-96-9
:Firocoxib
Description:
Firocoxib is a selective non-steroidal anti-inflammatory drug (NSAID) primarily used in veterinary medicine, particularly for the treatment of pain and inflammation in dogs and horses. It belongs to the class of cyclooxygenase-2 (COX-2) inhibitors, which work by selectively inhibiting the COX-2 enzyme, thereby reducing the production of prostaglandins that mediate inflammation and pain. Firocoxib is characterized by its relatively high selectivity for COX-2 over COX-1, which helps minimize gastrointestinal side effects commonly associated with traditional NSAIDs. The compound is typically administered orally and is available in various formulations, including tablets and paste. Its pharmacokinetics indicate a moderate half-life, allowing for once-daily dosing in many cases. Firocoxib is generally well-tolerated, but like all medications, it may have potential side effects, including gastrointestinal upset, renal effects, and hypersensitivity reactions. As with any medication, it is essential to use Firocoxib under veterinary guidance to ensure safety and efficacy for the intended use.
Formula:C17H20O5S
InChI:InChI=1S/C17H20O5S/c1-17(2)14(12-6-8-13(9-7-12)23(3,19)20)15(16(18)22-17)21-10-11-4-5-11/h6-9,11H,4-5,10H2,1-3H3
InChI key:InChIKey=FULAPETWGIGNMT-UHFFFAOYSA-N
SMILES:O(CC1CC1)C2=C(C(C)(C)OC2=O)C3=CC=C(S(C)(=O)=O)C=C3
Synonyms:- 2(5H)-Furanone, 3-(cyclopropylmethoxy)-5,5-dimethyl-4-4-(methylsulfonyl)phenyl-
- 3-(Cyclopropyl-methoxy)-5,5-Dimethy l-4-(4-methylsulfonyl)phenyl)-5H-furan-2-one
- 3-(Cyclopropylmethoxy)-5,5-Dimethyl-4-(4-Methylsulfonylphenyl)Furan-2- One
- 3-(Cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone
- 3-(cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]furan-2(5H)-one
- Equioxx
- Equixx
- Librens
- Ml 1785713
- Previcox
- Firocoxib
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Found 11 products.
2(5H)-Furanone, 3-(cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-
CAS:Formula:C17H20O5SPurity:99%Color and Shape:SolidMolecular weight:336.4027Firocoxib
CAS:Formula:C17H20O5SPurity:>95.0%(HPLC)(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:336.40Firocoxib
CAS:Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.Formula:C17H20O5SPurity:99.84%Color and Shape:SolidMolecular weight:336.4Firocoxib
CAS:Applications A selective cyclooxygenase-2-(COX-2) inhibitor. Anti-inflammatory; analgesic.
References McCann, M.E., et al.: Am. J. Vet. Res., 65, 503 (2004),Formula:C17H20O5SColor and Shape:NeatMolecular weight:336.4Firocoxib
CAS:COX-2 enzyme inhibitor; anti-inflammatoryFormula:C17H20O5SPurity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:336.40 g/molFirocoxib
CAS:3-(Cyclopropylmethoxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-oneFormula:C17H20O5SPurity:99%Molecular weight:336.43-(Cyclopropylmethoxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one
CAS:Formula:C17H20O5SPurity:99%Molecular weight:336.4
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