CAS 189955-89-3

Descyclopropylmethylfirocoxib

Description:

Descyclopropylmethylfirocoxib, identified by its CAS number 189955-89-3, is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the class of selective cyclooxygenase-2 (COX-2) inhibitors. This compound is primarily utilized for its analgesic and anti-inflammatory properties, making it effective in treating conditions such as arthritis and other inflammatory disorders. Its mechanism of action involves the selective inhibition of the COX-2 enzyme, which plays a crucial role in the synthesis of prostaglandins that mediate inflammation and pain. Descyclopropylmethylfirocoxib exhibits a favorable pharmacokinetic profile, including good oral bioavailability and a relatively long half-life, allowing for convenient dosing regimens. Additionally, it is characterized by a specific molecular structure that contributes to its potency and selectivity. As with other NSAIDs, potential side effects may include gastrointestinal issues, cardiovascular risks, and renal impairment, necessitating careful consideration in patients with pre-existing conditions. Overall, Descyclopropylmethylfirocoxib represents a significant advancement in the management of pain and inflammation.

Formula: C₁₃H₁₄O₅S

Synonyms:

• Descyclopropylmethylfirocoxib
• 2(5H)-Furanone, 3-hydroxy-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-

3-Hydroxy-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone

Controlled Product

CAS: 189955-89-3

Applications 3-Hydroxy-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone is a fluorescent metabolite of benzyloxy-substituted lactone cyclooxygenase-2 inhibitor DFB.
References Nicoll-Griffith, D., et al.: Drug Metab. Dispos., 32, 1509 (2004).

Formula: C₁₃H₁₄O₅S

Color and Shape: Neat

Molecular weight: 282.31

Ref: TR-H939540

Descyclopropylmethyl Firocoxib

CAS: 189955-89-3

Formula: C₁₃H₁₄O₅S

Molecular weight: 282.31

Ref: ST-EA-CP-F67001