CAS 18997-19-8
:Chloromethyl pivalate
Description:
Chloromethyl pivalate, with the CAS number 18997-19-8, is an organic compound characterized by its ester functional group and the presence of a chloromethyl group. It is derived from pivalic acid, which is a branched-chain carboxylic acid, and features a chloromethyl substituent that enhances its reactivity. This compound is typically a colorless to pale yellow liquid with a distinctive odor. It is soluble in organic solvents but has limited solubility in water due to its hydrophobic nature. Chloromethyl pivalate is primarily used as an intermediate in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. Its reactivity is attributed to the presence of the chloromethyl group, which can participate in nucleophilic substitution reactions. Safety precautions are necessary when handling this compound, as it may pose health risks, including irritation to the skin and respiratory system. Proper storage and handling protocols should be followed to mitigate any potential hazards associated with its use.
Formula:C6H11ClO2
InChI:InChI=1S/C6H11ClO2/c1-6(2,3)5(8)9-4-7/h4H2,1-3H3
InChI key:InChIKey=GGRHYQCXXYLUTL-UHFFFAOYSA-N
SMILES:C(C(C)(C)C)(OCCl)=O
Synonyms:- (2,2-Dimethyl-1-oxopropoxy)methyl chloride
- 2,2-Dimethylpropionic acid chloromethyl ester
- Chloromethyl 2,2-dimethylpropanoate
- Chloromethyl 2,2-dimethylpropionate
- Chloromethyl Pivalate [Amino-Protecting Agent]
- Chloromethyl trimethylacetate
- Methanol, chloro-, pivalate
- POM-Cl
- Pivalic acid, chloromethyl ester
- Pivaloyloxymethyl chloride
- Propanoic acid, 2,2-dimethyl-, chloromethyl ester
- [(tert-Butylcarbonyl)oxy]methyl chloride
- See more synonyms
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Found 8 products.
Chloromethyl Pivalate [Amino-Protecting Agent]
CAS:Formula:C6H11ClO2Purity:>99.0%(GC)Color and Shape:Colorless to Almost colorless clear liquidMolecular weight:150.60Chloromethyl pivalate, 97%
CAS:<p>Chloromethyl pivalate acts as an intermediate in the synthesis of active pharmaceutical ingredients. It is also involved in the acylation reaction with 9-(2-phosphonylmethoxyethyl)adenine. It serves as a protecting reagent used for the N-protection of amines. It is also employed in the preparation </p>Formula:C6H11ClO2Purity:97%Color and Shape:Clear colorless to pale yellow, LiquidMolecular weight:150.60Propanoic acid, 2,2-dimethyl-, chloromethyl ester
CAS:Formula:C6H11ClO2Purity:98%Color and Shape:LiquidMolecular weight:150.6033Chloromethyl pivalate
CAS:Chloromethyl pivalatePurity:99%Color and Shape:LiquidMolecular weight:150.60g/molChloromethyl Pivalate
CAS:Controlled Product<p>Applications Chloromethyl Pivalate is used in the synthesis of oxazolines used in the preparation of imidazolium triflates. Also used in the synthesis of Src Kinase inhibitors used as anti-tumor agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glorius, F. et al.: Chem. Comm., 22, 2704 (2002); Hennequin, L. et al.: J. Med. Chem., 49, 6465 (2006);<br></p>Formula:C6H11ClO2Color and Shape:NeatMolecular weight:150.6Chloromethyl pivalate
CAS:<p>Chloromethyl pivalate is an antimicrobial agent that belongs to the group of acyclic nucleoside phosphonates. It has been shown to inhibit the enzyme pyrazinoic acid synthase, which is involved in the biosynthesis of the pyrazinoic acid. Chloromethyl pivalate has significant cytotoxicity against cancer cells and can be used for the treatment of infectious diseases such as tuberculosis and leishmaniasis. Chloromethyl pivalate inhibits cell growth by binding to DNA and inhibiting protein synthesis. This drug also inhibits intermolecular hydrogen bonding, which may lead to its inhibition of bacterial growth.</p>Formula:C6H11ClO2Purity:Min. 95%Color and Shape:Colorless Slightly Yellow Clear LiquidMolecular weight:150.6 g/mol
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