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CAS 18997-57-4

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4-Methylumbelliferyl β-D-glucopyranoside

Description:
4-Methylumbelliferyl β-D-glucopyranoside (MUG) is a synthetic compound commonly used as a fluorogenic substrate in biochemical assays, particularly for the detection of β-glucosidase activity. It features a 4-methylumbelliferone moiety linked to a β-D-glucopyranoside unit, which upon hydrolysis by β-glucosidase releases the fluorescent 4-methylumbelliferone, allowing for sensitive detection. MUG is typically a white to off-white crystalline powder, soluble in water and organic solvents like methanol and dimethyl sulfoxide. Its fluorescence properties make it valuable in various applications, including enzyme assays, microbiological studies, and environmental monitoring. The compound is stable under normal laboratory conditions but should be stored in a cool, dry place, protected from light to prevent degradation. Safety data indicates that while MUG is generally considered low in toxicity, standard laboratory safety practices should be followed when handling the substance.
Formula:C16H18O8
InChI:InChI=1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15-,16-/m1/s1
InChI key:InChIKey=YUDPTGPSBJVHCN-YMILTQATSA-N
SMILES:CC=1C=2C(=CC(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=CC2)OC(=O)C1
Synonyms:
  • 2H-1-Benzopyran-2-one, 7-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-4-methyl-
  • 4-Methyl-coumarin-7-O-β-<span class="text-smallcaps">D</span>-glucoside
  • 4-Methylumbelliferone β-<span class="text-smallcaps">D</span>-glucoside
  • 4-Methylumbelliferyl glucoside
  • 4-Methylumbelliferyl β-<span class="text-smallcaps">D</span>-glucopyranoside
  • 4-Methylumbelliferyl-Beta-D-Glucopyranoside
  • 4-Methylumbelliferyl-β-<span class="text-smallcaps">D</span>-glucoside
  • 7-(β-<span class="text-smallcaps">D</span>-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one
  • Coumarin, 7-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-4-methyl-
  • 7-(β-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one
  • See more synonyms
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