CAS 1900-29-4

Trypacidin

Description:

Trypacidin, with the CAS number 1900-29-4, is a chemical compound that belongs to the class of antibiotics. It is primarily known for its antifungal properties, particularly effective against certain types of fungi. The compound exhibits a complex molecular structure, which contributes to its biological activity. Trypacidin functions by inhibiting the synthesis of essential components in fungal cell membranes, thereby disrupting their growth and reproduction. This mechanism makes it a valuable agent in the treatment of fungal infections. In terms of physical characteristics, Trypacidin is typically presented as a crystalline solid, and its solubility can vary depending on the solvent used. Safety and handling precautions are essential when working with this compound, as it may pose risks if not managed properly. Overall, Trypacidin is significant in the field of medicinal chemistry, particularly in the development of antifungal therapies.

Formula: C₁₈H₁₆O₇

InChI: InChI=1/C18H16O7/c1-9-5-12(22-2)15-13(6-9)25-18(16(15)20)11(17(21)24-4)7-10(19)8-14(18)23-3/h5-8H,1-4H3

InChI key: InChIKey=KMZYINVXZDQCKC-UHFFFAOYNA-N

SMILES: C(OC)(=O)C=1C2(C(=O)C=3C(O2)=CC(C)=CC3OC)C(OC)=CC(=O)C1

Synonyms:

• Spiro[benzofuran-2(3H),1′-[2,5]cyclohexadiene]-2′-carboxylic acid, 4,6′-dimethoxy-6-methyl-3,4′-dioxo-, methyl ester, (-)-
• 4-Methoxy-6-methylcoumaran-3-one-2-spiro-1′-(2′-carboxymethyl-6′-dimethoxycyclohexa-2′,5′-dien-4′-one)
• Trypacidin
• (-)-4,6'-Dimethoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester
• (-)-4,6-Dimethoxy-6-methyl-3,4-dioxospiro[benzofuran-2(3H),1-[2,5]cyclohexadiene]-2-carboxylic acid methyl ester

Trypacidin

CAS: 1900-29-4

Trypacidin, from A. fumigatus, kills B. subtilis, M. bovis, T. cruzi, T. gondii, and induces A549 cell lysis; boosts mouse survival in T. gondii model.

Formula: C₁₈H₁₆O₇

Color and Shape: Solid

Molecular weight: 344.319

Ref: TM-T35750

Trypacidin

CAS: 1900-29-4

Formula: C₁₈H₁₆O₇

Molecular weight: 344.3

Ref: 7W-GL4062

Trypacidin

CAS: 1900-29-4

Trypacidin is a chemical compound that belongs to the family of cross-linking agents. It has been found to have an inhibitory effect on the growth of wild-type strains and mutant strains of Aspergillus fumigatus, which are responsible for aspergillosis. Trypacidin also inhibits the growth of wild-type and mutant strains of Aspergillus terreus, which causes pulmonary aspergillosis. This chemical compound induces necrotic cell death in lung cells and mitochondrial membrane potential loss in heart cells. These effects are caused by apoptosis pathway disruption. The mode of action is believed to be through inhibition of acetate extraction from tissue culture media, resulting in an accumulation of protocatechuic acid.

Formula: C₁₈H₁₆O₇

Purity: Min. 95%

Molecular weight: 344.3 g/mol

Ref: 3D-BAA90029