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CAS 190273-81-5

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2-Amino-5-fluoroquinazoline

Description:
2-Amino-5-fluoroquinazoline is a heterocyclic organic compound characterized by a quinazoline core structure, which consists of a fused benzene and pyrimidine ring. The presence of an amino group at the 2-position and a fluorine atom at the 5-position contributes to its unique chemical properties. This compound typically exhibits moderate solubility in polar solvents and may show varying solubility in non-polar solvents. It is often studied for its potential biological activities, including antimicrobial and anticancer properties, due to the presence of the quinazoline scaffold, which is known for its pharmacological significance. The fluorine atom can enhance the compound's lipophilicity and metabolic stability, making it a subject of interest in medicinal chemistry. Additionally, 2-amino-5-fluoroquinazoline can participate in various chemical reactions, such as nucleophilic substitutions and coupling reactions, which are valuable in synthetic organic chemistry. Safety and handling precautions should be observed, as with any chemical substance, due to potential toxicity and reactivity.
Formula:C8H6FN3
InChI:InChI=1/C8H6FN3/c9-6-2-1-3-7-5(6)4-11-8(10)12-7/h1-4H,(H2,10,11,12)
SMILES:c1cc(c2c[nH]c(=N)nc2c1)F
Synonyms:
  • 2-Quinazolinamine,5-fluoro-(9CI)
  • 5-Fluoroquinazolin-2-Amine
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