CAS 19046-78-7

Adenylosuccinic acid

Description:

Adenylosuccinic acid, with the CAS number 19046-78-7, is a biochemical compound that plays a significant role in the purine nucleotide metabolism. It is a derivative of adenine and is involved in the synthesis of adenosine monophosphate (AMP) from inosine monophosphate (IMP). This compound is characterized by its structure, which includes an adenine moiety linked to a succinic acid component. Adenylosuccinic acid is typically found in biological systems, particularly in the context of cellular energy metabolism and nucleotide synthesis. It is soluble in water, which facilitates its participation in various enzymatic reactions within cells. The compound is also of interest in medical research, particularly in studies related to metabolic disorders and neurological conditions, as its levels can be indicative of certain biochemical pathways. Overall, adenylosuccinic acid is an important intermediate in the complex network of biochemical reactions that sustain cellular function and energy balance.

Formula: C₁₄H₁₈N₅O₁₁P

InChI: InChI=1S/C14H18N5O11P/c20-7(21)1-5(14(24)25)18-11-8-12(16-3-15-11)19(4-17-8)13-10(23)9(22)6(30-13)2-29-31(26,27)28/h3-6,9-10,13,22-23H,1-2H2,(H,20,21)(H,24,25)(H,15,16,18)(H2,26,27,28)/t5-,6+,9+,10+,13+/m0/s1

InChI key: InChIKey=OFBHPPMPBOJXRT-VWJPMABRSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N[C@@H](CC(O)=O)C(O)=O)N=CN3)O[C@H](COP(=O)(O)O)[C@H]1O

Synonyms:

• (2S)-2-[(9-{(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]tetrahydrofuran-2-yl}-9H-purin-6-yl)amino]butanedioic acid (non-preferred name)
• 2-[(9-{(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]tetrahydrofuran-2-yl}-9H-purin-6-yl)amino]butanedioic acid (non-preferred name)
• 6-Succino-5′-adenylic acid
• <span class="text-smallcaps">L</smallcap>-Aspartic acid, N-[9-(5-O-phosphono-β-<smallcap>D</span>-ribofuranosyl)-9H-purin-6-yl]-
• Adenylosuccinic acid
• Adenylsuccinic acid
• Aspartic acid, N-(9-β-<span class="text-smallcaps">D</smallcap>-ribofuranosyl-9H-purin-6-yl)-, 5′-phosphate, <smallcap>L</span>-
• Aspartic acid, N-(9-β-<span class="text-smallcaps">D</smallcap>-ribofuranosyl-9H-purin-6-yl)-, mono(dihydrogen phosphate) (ester), <smallcap>L</span>-
• Aspartyl adenylate
• L-Aspartic acid, N-(9-(5-O-phosphono-beta-D-ribofuranosyl)-9H-purin-6-yl)-
• N-[9-(5-O-Phosphono-β-<span class="text-smallcaps">D</smallcap>-ribofuranosyl)-9H-purin-6-yl]-<smallcap>L</span>-aspartic acid
• N-[9-(5-O-phosphonopentofuranosyl)-9H-purin-6-yl]aspartic acid
• Succinic acid, adenyl-
• Succinyl AMP
• Succinyladenosine 5′-monophosphate
• Succinyladenosine monophosphoric acid
• L-Aspartic acid, N-[9-(5-O-phosphono-β-D-ribofuranosyl)-9H-purin-6-yl]-
• N-[9-(5-O-Phosphono-β-D-ribofuranosyl)-9H-purin-6-yl]-L-aspartic acid
• Aspartic acid, N-(9-β-D-ribofuranosyl-9H-purin-6-yl)-, mono(dihydrogen phosphate) (ester), L-

Adenylosuccinic Acid

CAS: 19046-78-7

Formula: C₁₄H₁₈N₅O₁₁P

Molecular weight: 463.2934

Ref: IN-DA002EL4

Adenylosuccinic acid

CAS: 19046-78-7

Adenylosuccinic acid (Adenylosuccinate) is a purine nucleotide metabolic intermediate and a novel inducer of the Nrf2 cell protector.

Formula: C₁₄H₁₈N₅O₁₁P

Purity: 98%

Color and Shape: Solid

Molecular weight: 463.29

Ref: TM-T14129

Adenylosuccinic acid

CAS: 19046-78-7

Adenylosuccinic acid is an organic acid that is synthesized through the deamination of adenosine monophosphate. It is used in transfection experiments to inhibit polymerase chain reaction (PCR) and reverse transcriptase. Adenylosuccinic acid inhibits DNA synthesis by targeting enzymes such as the ribonucleotide reductase and the DNA polymerase β-subunit. Adenylosuccinic acid also inhibits protein synthesis, which may be due to its ability to inhibit energy metabolism, leading to cellular death. This drug has been shown to have a wide range of pharmacological effects, including anti-inflammatory, analgesic, and antifungal activity.

Formula: C₁₄H₁₈N₅O₁₁P

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 463.29 g/mol

Ref: 3D-FA159229