CAS 19057-60-4

(+)-Dioscin

Description:

(+)-Dioscin, with the CAS number 19057-60-4, is a naturally occurring steroidal saponin primarily extracted from various plant sources, particularly from the genus Dioscorea, commonly known as yam. This compound is characterized by its complex glycosidic structure, which includes a steroid backbone linked to sugar moieties. (+)-Dioscin exhibits a range of biological activities, including anti-inflammatory, antioxidant, and potential anticancer properties, making it of interest in pharmacological research. Its solubility is generally low in water but can dissolve in organic solvents, which is typical for many saponins. The compound's structure contributes to its ability to interact with cell membranes, influencing cellular processes. Additionally, (+)-Dioscin has been studied for its potential effects on cholesterol metabolism and its role in traditional medicine. As with many natural products, the extraction and purification processes can significantly affect its bioactivity and efficacy, highlighting the importance of sourcing and preparation methods in research and application.

Formula: C₄₅H₇₂O₁₆

InChI: InChI=1/C45H72O16/c1-19-9-14-45(54-18-19)20(2)30-28(61-45)16-27-25-8-7-23-15-24(10-12-43(23,5)26(25)11-13-44(27,30)6)57-42-39(60-41-36(52)34(50)32(48)22(4)56-41)37(53)38(29(17-46)58-42)59-40-35(51)33(49)31(47)21(3)55-40/h7,19-22,24-42,46-53H,8-18H2,1-6H3/t19-,20+,21+,22+,24+,25-,26+,27?,28+,29-,30+,31+,32+,33-,34-,35-,36-,37+,38-,39-,40+,41+,42-,43+,44+,45-/m1/s1

InChI key: InChIKey=VNONINPVFQTJOC-ZGXDEBHDSA-N

SMILES: C[C@@]12[C@@]3([C@](C[C@]1([C@]4([C@](CC2)([C@]5(C)C(=CC4)C[C@@H](O[C@H]6[C@H](O[C@H]7[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O7)[C@@H](O)[C@H](O[C@H]8[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O8)[C@@H](CO)O6)CC5)[H])[H])[H])(O[C@@]9([C@H]3C)CC[C@@H](C)CO9)[H])[H]

Synonyms:

• (3beta,14xi,25R)-spirost-5-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[6-deoxy-alpha-L-mannopyranosyl-(1->4)]-beta-D-glucopyranoside
• (3beta,25R)-spirost-5-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[6-deoxy-alpha-L-mannopyranosyl-(1->4)]-beta-D-glucopyranoside
• (3β,25R)-Spirost-5-en-3-yl O-6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl-(1→2)-O-[6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→4)]-β-<smallcap>D</span>-glucopyranoside
• 3-O-β-<span class="text-smallcaps">D</smallcap>-α-<smallcap>L</smallcap>-Rhamnopyranosyl(1→4)-[α-<smallcap>L</smallcap>-rhamnopyranosyl(1→2)]-β-<smallcap>D</span>-glucopyranoside-diosgenin
• Beta-D-Glucopyranoside,(3-Beta,25R)-Spirost-5-En-3-Ylo-6-Deoxy-Alpha-L-Mannop
• Collettiside III
• Collettisideiii
• Dioscin(P)
• Dioscine
• Diosgenin 3-O-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→2)-[α-<smallcap>L</smallcap>-rhamnopyranosyl-(1→4)]-β-<smallcap>D</span>-glucopyranoside
• Diosgenin 3-O-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→4)-[α-<smallcap>L</smallcap>-rhamnopyranosyl-(1→2)]-β-<smallcap>D</span>-glucopyranoside
• Diosgenin bis-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→2 and 1→4)-β-<smallcap>D</span>-glucopyranoside
• Paris III
• Parissaponin III
• Polyphyllin III
• Yranosyl-(1-2)-O-(6-Deoxy-Alpha-L-Mannopyranosyl)-(1-4))-
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→2)-O-[6-deoxy-α-<smallcap>L</span>-mannopyranosyl-(1→4)]-
• β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-
• Dioscin
• Diosgenin bis-α-L-rhamnopyranosyl-(1→2 and 1→4)-β-D-glucopyranoside
• (3β,25R)-Spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-β-D-glucopyranoside
• [(25R)-Spirosta-5-ene-3β-yl]2-O,4-O-bis(α-L-rhamnopyranosyl)-β-D-glucopyranoside
• (25R)-3β-[2-O,4-O-Bis(α-L-rhamnopyranosyl)-β-D-glucopyranosyloxy]spirosta-5-ene
• Dioscin Green Plants Extracts 19057-60-4 Dioscorea Nipponica Source
• Dioscin / Diosgenyl 2,4-Di-O-α-L-rhamnopyranosyl-β-D-glucopyranoside
• Diosgenin bis-alpha-L-rhamnopyranosyl)-(1-2 and 1-4)-beta-D-glucopyranoside
• Dioscin(Collettiside III)
• DIOSCIN(RG)
• Ccris 4123
• Dioscin 19057-60-4
• beta-D-Glucopyranoside, (3beta,25R)-spirost-5-en-3-yl o-6-deoxy-alpha-L-mannopyranosyl-(1-2)-o-(6-deoxy-alpha-L-mannopyranosyl-(1-4))-
• Dioscin (6ci,7ci,8ci)
• [(25R)-Spirosta-5-ene-3β-yl]2-O,4-O-di-α-L-rhamnopyranosyl-β-D-glucopyranoside
• Dioscin, 98%, from Dioscorea opposita Thunb.
• Yam Extract Dioscin
• Dioscin USP/EP/BP
• ioscin
• [(25R)-Spirost-5-en-3β-yl]2-O-(6-deoxy-α-L-mannopyranosyl)-4-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside

Dioscin

CAS: 19057-60-4

Formula: C₄₅H₇₂O₁₆

Purity: >95.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 869.06

Ref: 3B-D5167

Dioscin

CAS: 19057-60-4

Dioscin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₄₅H₇₂O₁₆

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 869.06

Ref: 11-3515S

Dioscin

CAS: 19057-60-4

Formula: C₄₅H₇₂O₁₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 869.0436

Ref: IN-DA00I2TD

Dioscin

CAS: 19057-60-4

Dioscin

Purity: ≥98%

Molecular weight: 869.04g/mol

Ref: 54-BUP00105

Dioscin

CAS: 19057-60-4

Dioscin

Purity: 98%

Molecular weight: 869.04g/mol

Ref: 54-OR1026166

Dioscin

CAS: 19057-60-4

Dioscin, a saponin extracted from the root of Polygonatum Zanlanscianense Pamp, can markedly inhibit proliferation of Hela cells, underwent apoptosis in dose- and time-dependent manner.

Formula: C₄₅H₇₂O₁₆

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 869.055

Ref: BP-BP0503

Dioscin

CAS: 19057-60-4

Ref: 7W-GC9259

Dioscin

CAS: 19057-60-4

Dioscin (Collettiside III) is a saponin with antitumor activities.

Formula: C₄₅H₇₂O₁₆

Purity: 99.85% - 99.87%

Color and Shape: Solid

Molecular weight: 869.04

Ref: TM-T6473

Dioscin

CAS: 19057-60-4

Formula: C₄₅H₇₂O₁₆

Molecular weight: 869.06

Ref: 4Z-G-157006

Dioscin

CAS: 19057-60-4

Natural glycoside

Formula: C₄₅H₇₂O₁₆

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 869.06

Ref: 5G-89648

Dioscin

CAS: 19057-60-4

Applications Dioscin, a natural steroid saponin that has been shown to promote anticancer activity against several forms of cancers. Dioscin induces cancer cell apoptosis through elevated oxidative stress mediated by downregulation of peroxiredoxins.
References Wang, Z., et al.: Land. Biosci., 13, 138 (2012); Shah, H.J., et al.: J. Anal. BIoanal. Tech., 3, 141 (2012); Zhao, X.M., et al.: Toxiciol. Lett., 214, 69 (2012);

Formula: C₄₅H₇₂O₁₆

Color and Shape: Neat

Molecular weight: 869.04

Ref: TR-D485230

Dioscin

CAS: 19057-60-4

Dioscin is a steroidal saponin, which is a naturally occurring compound found in various plants, notably in species such as Dioscorea nipponica and Dioscorea zingiberensis. These plants belong to the yam family, which are well-regarded for their medicinal properties. The mode of action of dioscin involves modulation of various biochemical pathways, including the suppression of inflammatory cytokines and inhibition of cancer cell proliferation. Additionally, dioscin has been shown to promote apoptosis in cancer cells through the activation of caspases and disruption of mitochondrial function.

Formula: C₄₅H₇₂O₁₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 869.05 g/mol

Ref: 3D-OD11563

Dioscin

CAS: 19057-60-4

Dioscin is a type of steroidal saponin, which is a naturally occurring glycoside. It is primarily derived from various plant sources, including members of the Dioscorea family, such as wild yam species. Dioscin exhibits its biological activity through modulation of multiple molecular pathways, notably exhibiting anti-inflammatory, antioxidative, and antiproliferative effects.

Formula: C₄₅H₇₂O₁₆

Purity: Min. 98.0 Area-%

Molecular weight: 869.04 g/mol

Ref: 3D-Q-100228