CAS 19063-55-9

6-Bromo-2H-1-benzopyran-2-one

Description:

6-Bromo-2H-1-benzopyran-2-one, also known as 6-bromo coumarin, is a chemical compound belonging to the coumarin family, characterized by its fused benzene and pyrone rings. This compound typically appears as a pale yellow to white crystalline solid. It is known for its aromatic properties and is often used in organic synthesis and as a fluorescent probe in various applications. The presence of the bromine atom at the 6-position enhances its reactivity, making it useful in further chemical modifications. 6-Bromo-2H-1-benzopyran-2-one exhibits moderate solubility in organic solvents, such as ethanol and acetone, but is less soluble in water. Its structure allows for potential applications in medicinal chemistry, particularly in the development of pharmaceuticals due to its biological activity, including antimicrobial and anticancer properties. As with many brominated compounds, it is important to handle it with care due to potential toxicity and environmental concerns.

Formula: C₉H₅BrO₂

InChI: InChI=1S/C9H5BrO2/c10-7-2-3-8-6(5-7)1-4-9(11)12-8/h1-5H

InChI key: InChIKey=XXRJDOQENVGLJT-UHFFFAOYSA-N

SMILES: BrC=1C=C2C(OC(=O)C=C2)=CC1

Synonyms:

• 2H-1-benzopyran-2-one, 6-bromo-
• 6-Bromo-2H-1-benzopyran-2-one
• 6-Bromo-2H-chromen-2-one
• 6-Bromochromene-2-one
• Coumarin, 6-bromo-
• NSC 146624
• 6-Bromocoumarin

2H-1-Benzopyran-2-one, 6-bromo-

CAS: 19063-55-9

Formula: C₉H₅BrO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 225.0388

Ref: IN-DA002EPD

6-Bromochromen-2-one

CAS: 19063-55-9

6-Bromochromen-2-one

Purity: 97%

Molecular weight: 225.04g/mol

Ref: 54-OR90106

6-Bromo-2H-chromen-2-one

CAS: 19063-55-9

Formula: C₉H₅BrO₂

Purity: >98.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 225.04

Ref: 3B-B6613

6-Bromochromen-2-one

CAS: 19063-55-9

Formula: C₉H₅BrO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 225.041

Ref: 10-F076818

6-Bromocoumarin

CAS: 19063-55-9

6-Bromocoumarin is a synthetic heterocycle that has been shown to be effective in the treatment of cervical cancer. It inhibits cholinesterase enzymes and causes cross-coupling reactions, which leads to DNA damage. 6-Bromocoumarin also displays anti-inflammatory properties and has been shown to inhibit phosphatases, as well as progesterone receptor in human lung cells. In addition, it displays fluorescence properties and has been shown to segregate into two phases when mixed with malonic acid. The mechanism of action involves the following steps: 1) 6-bromocoumarin reacts with the enzyme cholinesterase; 2) this reaction releases acetylcholine from the enzyme; 3) acetylcholine binds to muscarinic receptors on cells, leading to an increase in intracellular calcium levels; 4) increased intracellular calcium levels activate phosphatases, which are proteins that break down proteins

Formula: C₉H₅BrO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 225.04 g/mol

Ref: 3D-FB66420