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CAS 190775-14-5

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(LYS15)-AMYLOID BETA-PROTEIN (15-21)

Description:
(LYS15)-Amyloid beta-protein (15-21) is a peptide fragment derived from the amyloid precursor protein, specifically representing amino acids 15 to 21 of the amyloid beta peptide. This peptide is of significant interest in Alzheimer's disease research, as amyloid beta aggregates are implicated in the pathogenesis of the disease. The modification at lysine 15 (LYS15) suggests that this peptide may have altered properties compared to the unmodified form, potentially affecting its aggregation behavior, solubility, and interaction with other biomolecules. Characteristically, this peptide is typically hydrophilic due to the presence of charged and polar amino acids, which can influence its biological activity and stability. It may also exhibit a propensity to form beta-sheet structures, a hallmark of amyloid fibrils. Research involving this peptide often focuses on its role in neurotoxicity, aggregation kinetics, and potential therapeutic interventions aimed at modulating amyloid beta-related processes in neurodegenerative diseases.
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