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CAS 190792-74-6

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(3S,4S)-N-Boc-3-amino-4-hydroxypyrrolidine

Description:
(3S,4S)-N-Boc-3-amino-4-hydroxypyrrolidine is a chiral pyrrolidine derivative characterized by the presence of a tert-butyloxycarbonyl (Boc) protecting group on the nitrogen atom, an amino group at the 3-position, and a hydroxyl group at the 4-position of the pyrrolidine ring. This compound is typically used in organic synthesis, particularly in the development of pharmaceuticals and biologically active molecules, due to its ability to serve as a building block for more complex structures. The stereochemistry indicated by the (3S,4S) configuration suggests that it has specific spatial arrangements that can influence its reactivity and interactions in biological systems. The presence of both an amino and a hydroxyl group contributes to its potential for hydrogen bonding, which can affect solubility and reactivity. Additionally, the Boc group can be removed under acidic conditions, allowing for further functionalization of the amino group. Overall, this compound is significant in medicinal chemistry and synthetic organic chemistry for its versatile reactivity and structural features.
Formula:C9H18N2O3
Synonyms:
  • 1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester,(3S,4S)-
  • (3S,4S)-3-Amino-4-hydroxypyrrolidine-1-carboxylic acid tert-butyl ester
  • (3S,4S)-tert-Butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate
  • (3S,4S)-N-3-amino-4-hydroxypyrrolidine
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