CAS 1909225-07-5

Benzamide, 2-(dimethylamino)-N-[[[4-[(4,6-dimethyl-2-pyrimidinyl)oxy]-3-methylphenyl]amino]carbonyl]-

Description:

Benzamide, 2-(dimethylamino)-N-[[[4-[(4,6-dimethyl-2-pyrimidinyl)oxy]-3-methylphenyl]amino]carbonyl]- is a complex organic compound characterized by its structural features, which include a benzamide core substituted with a dimethylamino group and a pyrimidine moiety. This compound typically exhibits properties associated with both amides and aromatic systems, such as moderate solubility in organic solvents and potential interactions with biological targets due to its ability to form hydrogen bonds. The presence of the dimethylamino group suggests basicity, which may influence its reactivity and interaction with other molecules. Additionally, the pyrimidine ring contributes to its potential pharmacological activity, as many pyrimidine derivatives are known for their roles in medicinal chemistry. The compound's specific applications and behavior in biological systems would depend on its precise molecular interactions, stability, and the presence of functional groups that can participate in various chemical reactions. Overall, this compound represents a class of molecules that may have significance in drug development and chemical research.

Formula: C₂₃H₂₅N₅O₃

Synonyms:

• Benzamide, 2-(dimethylamino)-N-[[[4-[(4,6-dimethyl-2-pyrimidinyl)oxy]-3-methylphenyl]amino]carbonyl]-

TRPM7-IN-1

CAS: 1909225-07-5

TRPM7-IN-1 (compound SUD) is a benzamide-urea derivative and an effective inhibitor of TRPM7. This compound induces cell cycle arrest and apoptosis in MCF-7 and BGC-823 cells, reducing their migration capabilities. It decreases vimentin expression while increasing E-cadherin expression. TRPM7-IN-1 reduces TRPM7-like currents and inhibits TRPM7 expression by activating the PI3K/Akt signaling pathway. This compound shows potential as a therapeutic agent for reducing breast and gastric cancer metastasis by targeting TRPM7 expression and activity.

Formula: C₂₃H₂₅N₅O₃

Color and Shape: Solid

Molecular weight: 419.48

Ref: TM-T201413