CAS 1909226-00-1

BDA-366

CAS: 1909226-00-1

BDA-366

Purity: ≥98%

Molecular weight: 423.5g/mol

Ref: 54-BUP02384

BDA-366

CAS: 1909226-00-1

BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies its

Formula: C₂₄H₂₉N₃O₄

Purity: 98.61%

Color and Shape: Soild

Molecular weight: 423.5

Ref: TM-T6778

BDA-366

CAS: 1909226-00-1

BDA-366 is a potential anticancer agent that inhibits apoptosis by inhibiting the release of cytochrome c from mitochondria. It has shown potent antitumor activity in vitro and in vivo and can be used to treat cancer. BDA-366 binds to the bcl-2 protein and prevents it from forming heterodimers with pro-apoptotic proteins such as bax, resulting in inhibition of mitochondrial membrane depolarization. BDA-366 also inhibits the production of pro-apoptotic proteins such as cytochrome c, which leads to cell death.

Formula: C₂₄H₂₉N₃O₄

Purity: Min. 95%

Molecular weight: 423.5 g/mol

Ref: 3D-JBD22600