CAS 191-30-0

Dibenzo[a,l]pyrene

Description:

Dibenzo[a,l]pyrene is a polycyclic aromatic hydrocarbon (PAH) characterized by its complex fused ring structure, consisting of five benzene rings. It is known for its high molecular weight and is classified as a potent carcinogen. This compound is typically found in products of incomplete combustion, such as tobacco smoke, grilled meats, and various industrial processes. Dibenzo[a,l]pyrene is insoluble in water but soluble in organic solvents, which influences its environmental persistence and bioaccumulation potential. Its chemical structure contributes to its stability and resistance to degradation, making it a concern for environmental health. The compound has been studied for its mutagenic and carcinogenic properties, particularly in relation to DNA damage and the formation of adducts. Due to its hazardous nature, dibenzo[a,l]pyrene is subject to regulatory scrutiny, and its presence in the environment is monitored to mitigate potential health risks. Understanding its behavior and effects is crucial for assessing environmental contamination and human exposure.

Formula: C₂₄H₁₄

InChI: InChI=1S/C24H14/c1-2-8-18-16(6-1)14-17-13-12-15-7-5-11-20-19-9-3-4-10-21(19)24(18)23(17)22(15)20/h1-14H

InChI key: InChIKey=JNTHRSHGARDABO-UHFFFAOYSA-N

SMILES: C12=C3C=4C(C=5C1=C(C=CC2=CC=6C3=CC=CC6)C=CC5)=CC=CC4

Synonyms:

• 1,2,9,10-Dibenzopyrene
• 1,2:3,4-Dibenzopyrene
• 2,3:4,5-Dibenzpyrene
• 4,5,6,7-Dibenzpyrene
• 7A,10A-Dihydronaphtho[1,2,3,4-Pqr]Tetraphene
• Ba 51-090462
• Dibenzo(A,L)Pyrene
• Dibenzo[a,l]pyrene (purity)
• Dibenzo[def,p]chrysene
• NSC 90324
• Naphtho[1,2,3,4-Pqr]Tetraphene

Dibenzo[def,p]chrysene

CAS: 191-30-0

Formula: C₂₄H₁₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 302.3680

Ref: IN-DA002EZK

Dibenzo[a,l]pyrene 10 µg/mL in Acetonitrile

CAS: 191-30-0

Formula: C₂₄H₁₄

Color and Shape: Single Solution

Molecular weight: 302.37

Ref: 04-L20725000AL

Dibenzo[a,l]pyrene

Controlled Product

CAS: 191-30-0

Formula: C₂₄H₁₄

Color and Shape: Neat

Molecular weight: 302.37

Ref: 04-C20725000

PAH Mixture 932 200 µg/mL in Dichloromethane

Controlled Product

CAS: 120-12-7, 129-00-0, 189-55-9, 189-64-0, 191-24-2, 191-30-0, 192-65-4, 192-97-2, 193-39-5, 198-55-0, 205-99-2, 206-44-0, 207-08-9, 208-96-8, 218-01-9, 50-32-8, 53-70-3, 56-55-3, 83-32-9, 85-01-8, 86-73-7, 91-20-3

Formula: C₁₂H₁₀

Color and Shape: Mixture

Molecular weight: 154.21

Ref: 04-GA09000932DI

PAH-Mix 183 10 µg/mL in Cyclohexane

Controlled Product

CAS: 189-55-9, 189-64-0, 191-24-2, 191-30-0, 192-65-4, 193-39-5, 205-12-9, 205-82-3, 205-99-2, 207-08-9, 218-01-9, 27208-37-3, 3697-24-3, 50-32-8, 53-70-3, 56-55-3

Formula: C₁₉H₁₄

Color and Shape: Mixture

Molecular weight: 242.31

Ref: 04-LA20950183CY

OEKO-TEX PAH Mixture 575 500 µg/mL in Dichloromethane

Controlled Product

CAS: 120-12-7, 129-00-0, 189-55-9, 189-64-0, 191-24-2, 191-30-0, 192-65-4, 192-97-2, 193-39-5, 205-82-3, 205-99-2, 206-44-0, 207-08-9, 208-96-8, 218-01-9, 2381-21-7, 27208-37-3, 50-32-8, 53-70-3, 56-55-3, 83-32-9, 85-01-8, 86-73-7, 91-20-3

Color and Shape: Mixture

Ref: 04-A50000575DI

Dibenzo[a,l]pyrene 10 µg/mL in Cyclohexane

CAS: 191-30-0

Formula: C₂₄H₁₄

Color and Shape: Single Solution

Molecular weight: 302.37

Ref: 04-L20725000CY

Dibenzo[def,p]chrysene

Controlled Product

CAS: 191-30-0

Applications An active metabolite from inhalation and dermal exposure to polycyclic aromatics hydrocarbons found in hot mix asphalt paving workers. DBC is the most potent tumorigen that has been identified to date. Dibenzo[def,p]chrysene (DBC) is a carcinogen and should be handled with caution.
References Anderson, L., et al.: Toxicol. Appl. Pharmacol., 199, 85 (2004), Yu, Z., et al.: Cancer Res., 66, 755 (2006), Shen, J., et al.: Toxicol. Sci., 95, 313 (2007),

Formula: C₂₄H₁₄

Color and Shape: Off-White

Molecular weight: 302.37

Ref: TR-D416945

Dibenzo[def,p]chrysene-d8 (Major)

Controlled Product

CAS: 191-30-0

Applications Labelled Dibenzo[a,l]pyrene (D416945). An active metabolite from inhalation and dermal exposure to polycyclic aromatics hydrocarbons in hot mix asphalt paving workers. DBC is the most potent tumorigen that has been identified to date. Dibenzo[def,p]chrysene (DBC) is a carcinogen and should be handled with appropriate caution.
References Anderson, L., et al.: Toxicol. Appl. Pharmacol., 199, 85 (2004), Yu, Z., et al.: Cancer Res., 66, 755 (2006), Shen, J., et al.: Toxicol. Sci., 95, 313 (2007),

Formula: C₂₄H₆D₈

Color and Shape: Neat

Molecular weight: 310.42

Ref: TR-D416947

Dibenzo[def,p]chrysene-d14 (Major)

Controlled Product

CAS: 191-30-0

Applications Labelled Dibenzo[a,l]pyrene (D416945). An active metabolite from inhalation and dermal exposure to polycyclic aromatics hydrocarbons in hot mix asphalt paving workers. DBC is the most potent tumorigen that has been identified to date. Dibenzo[def,p]chrysene (DBC) is a carcinogen and should be handled with appropriate caution.
References Anderson, L., et al.: Toxicol. Appl. Pharmacol., 199, 85 (2004), Yu, Z., et al.: Cancer Res., 66, 755 (2006), Shen, J., et al.: Toxicol. Sci., 95, 313 (2007),

Formula: C₂₄D₁₄

Color and Shape: Neat

Molecular weight: 316.45

Ref: TR-D416948

Dibenzo[def,p]chrysene

CAS: 191-30-0

Dibenzo[def,p]chrysene is a polycyclic aromatic hydrocarbon (PAH) that has been shown to be genotoxic and carcinogenic in animals. It has also been found to have potential as a biomarker for exposure. The toxic effects of dibenzo[def,p]chrysene are due to its ability to induce oxidative stress and cause DNA damage, leading to cell death. Dibenzo[def,p]chrysene inhibits transcriptional regulation by binding to the polymerase chain reaction (PCR) enzyme, cytochrome p450, and pro-apoptotic protein. Dibenzo[def,p]chrysene can also activate detoxification enzymes such as glutathione S-transferases and quinone reductases. This PAH is metabolized through phase II conjugation with glutathione or glucuronides. Listed below are some biological properties of diben

Formula: C₂₄H₁₄

Purity: Min. 95%

Molecular weight: 302.37 g/mol

Ref: 3D-FD21528

Method DM 471 PAH Mixture 361 10 µg/mL in Acetonitrile

Controlled Product

CAS: 129-00-0, 189-55-9, 189-64-0, 191-24-2, 191-30-0, 192-65-4, 193-39-5, 205-99-2, 207-08-9, 218-01-9, 50-32-8, 53-70-3, 56-55-3

Color and Shape: Mixture

Ref: 04-A50000361AL