CymitQuimica logo

CAS 1912445-55-6

:

BMS-986195

Description:
BMS-986195, with the CAS number 1912445-55-6, is a chemical compound that has garnered attention in pharmaceutical research, particularly in the context of treating autoimmune diseases. It is classified as a selective inhibitor of the enzyme Janus kinase 1 (JAK1), which plays a crucial role in the signaling pathways of various cytokines involved in inflammatory responses. The compound's mechanism of action involves modulating immune responses, making it a potential therapeutic agent for conditions such as rheumatoid arthritis and other inflammatory disorders. BMS-986195 is characterized by its specific binding affinity to JAK1, which helps to minimize off-target effects associated with broader JAK inhibitors. In preclinical and clinical studies, it has demonstrated a favorable safety profile and efficacy in reducing disease activity. As with many investigational drugs, ongoing research is essential to fully understand its pharmacokinetics, pharmacodynamics, and long-term effects in diverse patient populations.
Formula:C20H23FN4O2
Synonyms:
  • CPD1640
  • Branebrutinib (BMS-986195)
  • BMS-986195 USP/EP/BP
  • (S)-4-(3-(but-2-ynamido)piperidin-1-yl)-5-fluoro-2,3-dimethyl-1H-indole-7-carboxamide
  • BMS-986195; BMS986195; BMS986195
  • 1H-Indole-7-carboxamide, 5-fluoro-2,3-dimethyl-4-[(3S)-3-[(1-oxo-2-butyn-1-yl)amino]-1-piperidinyl]-
  • BMS-986195
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 4 products.