CAS 191338-86-0

Ac-Ile-Glu-Thr-Asp-aldehyde (pseudo acid)

Description:

Ac-Ile-Glu-Thr-Asp-aldehyde, also known as a pseudo acid, is a synthetic peptide derivative characterized by its unique sequence of amino acids: isoleucine (Ile), glutamic acid (Glu), threonine (Thr), and aspartic acid (Asp), with an aldehyde functional group. This compound is typically used in biochemical research and pharmaceutical applications due to its potential role in peptide synthesis and modification. The presence of the aldehyde group suggests reactivity that can be exploited in various chemical reactions, including condensation and cross-linking with other biomolecules. The acetylation at the amino terminus enhances its stability and solubility, making it suitable for biological studies. Its structure allows for specific interactions with biological targets, which can be crucial for understanding peptide behavior in physiological conditions. As with many peptides, its properties, such as solubility, stability, and biological activity, can be influenced by factors like pH and temperature. Overall, Ac-Ile-Glu-Thr-Asp-aldehyde serves as a valuable tool in the fields of biochemistry and medicinal chemistry.

Formula: C₂₁H₃₄N₄O₁₀

Ac-Ile-Glu-Thr-Asp-H (aldehyde)

CAS: 191338-86-0

Ac-Ile-Glu-Thr-Asp-H (aldehyde) is a peptide fragment of the human calcitonin gene. It is a research tool used in immunology and cell biology. Ac-Ile-Glu-Thr-Asp-H (aldehyde) binds to different types of ion channels, including ligand gated ion channels, voltage gated ion channels, and receptor activated ion channels. Ac-Ile-Glu-Thr-Asp-H (aldehyde) can also bind to membrane receptors such as the muscarinic acetylcholine receptor and the alpha adrenergic receptor. Acetylcholine is a neurotransmitter that activates the muscarinic acetylcholine receptor, which leads to an increase in intracellular levels of cyclic AMP. Alpha adrenergic receptors are located on the surface of blood vessels and activate vasoconstriction by inhibiting adenylyl cyclase activity.

Formula: C₂₁H₃₄N₄O₁₀

Purity: Min. 95%

Molecular weight: 502.52 g/mol

Ref: 3D-ICA-3196-V

Ac-​IETD-​CHO

CAS: 191338-86-0

Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase 8, which also impedes Fas-mediated apoptosis, hemorrhagic conditions, and liver failure.

Formula: C₂₁H₃₄N₄O₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 502.52

Ref: TM-T78586

Ac-Ile-Glu-Thr-Asp-aldehyde (pseudo acid)

CAS: 191338-86-0

Ac-Ile-Glu-Thr-Asp-aldehyde (pseudo acid) is a neurotrophic factor that plays an important role in the development and function of the nervous system. It stimulates the production of other neurotrophic factors such as NGF, BDNF, and GDNF. This protein has been shown to be involved in a number of autoimmune diseases, including multiple sclerosis and rheumatoid arthritis. Ac-Ile-Glu-Thr-Asp-aldehyde (pseudo acid) is also known to reduce neuronal death by binding to toll receptors on neurons and activating mitogen activated protein kinases. Acetylcholine esterase activity can also be inhibited by this protein. Acetylcholine esterase is responsible for breaking down acetylcholine, which is a neurotransmitter that transmits nerve impulses across the synapses between neurons. The inhibition of this enzyme leads to an increase in acetylcholine levels and increased transmission of

Formula: C₂₁H₃₄N₄O₁₀

Purity: Min. 95%

Molecular weight: 502.52 g/mol

Ref: 3D-FA111074