CAS 191348-16-0

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-[hydroxy(phenylmethoxy)phosphinyl]-L-tyrosine

Description:

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-[hydroxy(phenylmethoxy)phosphinyl]-L-tyrosine, commonly referred to by its CAS number 191348-16-0, is a synthetic compound that serves as a phosphonate derivative of the amino acid L-tyrosine. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is commonly used in peptide synthesis to protect the amino group of amino acids. The presence of the phosphinyl group indicates that it may exhibit unique reactivity and biological activity, potentially influencing its role in biochemical pathways or as a pharmaceutical agent. The hydroxy(phenylmethoxy) substituent suggests that the compound may have enhanced solubility and stability, making it suitable for various applications in medicinal chemistry. Its structural complexity allows for potential interactions with biological targets, which could be of interest in drug development. Overall, this compound exemplifies the intersection of organic chemistry and biochemistry, highlighting the importance of functional groups in determining the properties and reactivity of chemical substances.

Formula: C₃₁H₂₈NO₈P

InChI: InChI=1S/C31H28NO8P/c33-30(34)29(18-21-14-16-23(17-15-21)40-41(36,37)39-19-22-8-2-1-3-9-22)32-31(35)38-20-28-26-12-6-4-10-24(26)25-11-5-7-13-27(25)28/h1-17,28-29H,18-20H2,(H,32,35)(H,33,34)(H,36,37)/t29-/m0/s1

InChI key: InChIKey=WNFKGEXQEWKECX-LJAQVGFWSA-N

SMILES: C(OC(N[C@@H](CC1=CC=C(OP(OCC2=CC=CC=C2)(=O)O)C=C1)C(O)=O)=O)C3C=4C(C=5C3=CC=CC5)=CC=CC4

Synonyms:

• (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[4-[hydroxy(phenylmethoxy)phosphoryl]oxyphenyl]propanoic acid
• (2S)-3-[4-(benzyloxy-hydroxy-phosphoryl)oxyphenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
• <span class="text-smallcaps">L</span>-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, phenylmethyl hydrogen phosphate (ester)
• <span class="text-smallcaps">L</span>-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-[hydroxy(phenylmethoxy)phosphinyl]-
• Fmoc-<span class="text-smallcaps">L</span>-O-benzylphosphotyrosine
• Fmoc-L-Tyr(Po(Obzl)Oh)-Oh
• Fmoc-O-Benzylphospho-L-Tyrosine
• Fmoc-Tyr(Ho3Bzl)-Oh
• Fmoc-Tyr(Hpo3Bzl)-Oh
• Fmoc-Tyr(PO(OBzl))-OH
• Fmoc-Tyr[Po(Obz)Oh]-Oh
• Fmoc-Tyrosine(Po(Obzl)Oh)-Oh
• L-Phosphotyrosine
• N-Fmoc-O-benzyl-L-phosphotyrosine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-[hydroxy(phenylmethoxy)phosphinyl]-<span class="text-smallcaps">L</span>-tyrosine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-[hydroxy(phenylmethoxy)phosphinyl]-L-tyrosine
• L-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, phenylmethyl hydrogen phosphate (ester)
• Fmoc-L-O-benzylphosphotyrosine

Fmoc-Tyr(PO(OBzl)OH)-OH

CAS: 191348-16-0

Alternative to Fmoc-Tyr(PO₃(MDPSE)₂)-OH.

Formula: C₃₁H₂₈NO₈P

Purity: 97.2%

Color and Shape: White Powder

Molecular weight: 573.54

Ref: 01-4038299

L-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-[hydroxy(phenylmethoxy)phosphinyl]-

CAS: 191348-16-0

Formula: C₃₁H₂₈NO₈P

Purity: 97%

Color and Shape: Solid

Molecular weight: 573.5297

Ref: IN-DA002F5Y

(2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(((benzyloxy)(hydroxy)phosphoryl)oxy)phenyl)propanoic acid

CAS: 191348-16-0

(2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(((benzyloxy)(hydroxy)phosphoryl)oxy)phenyl)propanoic acid

Purity: 97%

Molecular weight: 573.53g/mol

Ref: 54-OR76050

Fmoc-O-benzylphospho-L-tyrosine

CAS: 191348-16-0

Fmoc-O-benzylphospho-L-tyrosine is a synthetic amino acid that can be used as a molecular model for tyrosine kinases. Fmoc-O-benzylphospho-L-tyrosine has been shown to inhibit the activity of tyrosine phosphatases. It also binds to phosphate groups in the presence of calcium ions, which may help to immobilize it and prevent its hydrolysis by phosphatases. The binding constants of Fmoc-O-benzylphospho-L-tyrosine with these phosphate groups are determined using analytical chemistry. Fmoc-O-benzylphospho-L-tyrosine has been found to bind to immobilized cells and be expressed at high levels in mammalian cells.

Formula: C₃₁H₂₈NO₈P

Purity: Min. 97 Area-%

Color and Shape: White Powder

Molecular weight: 573.53 g/mol

Ref: 3D-FF47780

(2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(((benzyloxy)(hydroxy)phosphoryl)oxy)phenyl)propanoic acid

CAS: 191348-16-0

Purity: 97%

Molecular weight: 573.5380249

Ref: 10-F790976