CAS 1914971-04-2

TCO4-PEG3-Maleimide

Description:

TCO4-PEG3-Maleimide is a chemical compound that features a combination of a maleimide functional group and a polyethylene glycol (PEG) moiety, specifically with a four-carbon ring (TCO) structure. The maleimide group is known for its ability to undergo Michael addition reactions, making it useful in bioconjugation and labeling applications, particularly in the context of attaching biomolecules such as proteins or peptides. The PEG segment enhances the solubility and biocompatibility of the compound, which is advantageous for applications in drug delivery and biomedical research. The presence of the TCO moiety allows for specific reactions with certain dienophiles, facilitating controlled conjugation processes. Overall, TCO4-PEG3-Maleimide is characterized by its reactivity, solubility, and utility in various chemical and biological applications, particularly in the fields of medicinal chemistry and materials science. Its unique structure enables it to serve as a versatile tool for researchers working on targeted therapies and diagnostics.

Formula: C₂₄H₃₇N₃O₈

Synonyms:

• TCO4-PEG3-Maleimide
• (E)-Cyclooct-4-en-1-yl (15-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-13-oxo-3,6,9-trioxa-12-azapentadecyl)carbamate

TCO-PEG3-Maleimide

CAS: 1914971-04-2

Formula: C₂₄H₃₇N₃O₈

Purity: >90.0%(HPLC)

Color and Shape: Colorless to Light orange to Yellow clear liquid

Molecular weight: 495.57

Ref: 3B-T3948

TCO4-PEG3-Maleimide

CAS: 1914971-04-2

TCO4-PEG3-Maleimide is a PROTAC linker of the PEG class. It contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, respectively, or participate in "thiol-Michael" addition.

Formula: C₂₄H₃₇N₃O₈

Molecular weight: 495.57

Ref: TM-T208652