CAS 19171-19-8: Pomalidomide

Description: Pomalidomide is an immunomodulatory drug primarily used in the treatment of multiple myeloma and certain other hematological malignancies. It belongs to a class of compounds known as thalidomide analogs, which exert their effects through various mechanisms, including modulation of the immune system and inhibition of tumor growth. The chemical formula of pomalidomide is C13H11N3O4S, and it features a unique structure that includes a phthalimide ring, a sulfonamide group, and an aromatic side chain. Pomalidomide is known for its ability to enhance T-cell and natural killer cell activity, as well as its anti-angiogenic properties, which help to inhibit the formation of new blood vessels that tumors require for growth. The drug is typically administered orally and has a relatively long half-life, allowing for convenient dosing schedules. However, it is associated with potential side effects, including hematological toxicities, and requires careful monitoring during treatment. Overall, pomalidomide represents a significant advancement in targeted cancer therapies.

Formula: C₁₃H₁₁N₃O₄

InChI: InChI=1S/C13H11N3O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5,14H2,(H,15,17,18)

InChI key: InChIKey=UVSMNLNDYGZFPF-UHFFFAOYSA-N

SMILES: O=C1C=2C=CC=C(N)C2C(=O)N1C3C(=O)NC(=O)CC3

Synonyms:

• 1H-Isoindole-1,3(2H)-dione, 4-amino-2-(2,6-dioxo-3-piperidinyl)-
• 2-(2,6-Dioxopiperidin-3-yl)-4-amino-isoindole-1,3-dione
• 3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide
• 4-Amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
• 4-Amino-2-(2,6-dioxo-3-piperidinyl)isoindole-1,3-dione
• 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione
• 4-Amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
• 4-Amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione
• 4-amino-2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione
• Actimid
• Cc 4047
• Imnovid
• Phthalimide, 3-amino-N-(2,6-dioxo-3-piperidyl)-
• Pomalyst

Pomalidomide

CAS: 19171-19-8

• Formula: C₁₃H₁₁N₃O₄
• Purity: >98.0%(HPLC)
• Color and Shape: White to Yellow to Green powder to crystaline
• Molecular weight: 273.25

1H-Isoindole-1,3(2H)-dione, 4-amino-2-(2,6-dioxo-3-piperidinyl)-

CAS: 19171-19-8

• Formula: C₁₃H₁₁N₃O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 273.2441

Pomalidomide

CAS: 19171-19-8

• Purity: 98.79%
• Molecular weight: 273.24g/mol

Pomalidomide

CAS: 19171-19-8

• Purity: 98+%
• Molecular weight: 273.24g/mol

Pomalidomide

CAS: 19171-19-8

• Formula: C₁₃H₁₁N₃O₄
• Color and Shape: Yellow Solid
• Molecular weight: 273.25

Pomalidomide

CAS: 19171-19-8

• Formula: C₁₃H₁₁N₃O₄
• Color and Shape: Neat
• Molecular weight: 273.24

Pomalidomide

CAS: 19171-19-8

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₃H₁₁N₃O₄
• Color and Shape: Powder, Yellow to green
• Molecular weight: 273.25

4-Amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

CAS: 19171-19-8

• Purity: 98.00%
• Color and Shape: Solid
• Molecular weight: 273.24798583984375

Pomalidomide-d4

CAS: 19171-19-8

• Formula: C₁₃H₇N₃O₄D₄
• Color and Shape: White To Off-White Solid
• Molecular weight: 277.27

Pomalidomide

CAS: 19171-19-8

Pomalidomide (CC-4047) is an anti-angiogenic and immunomodulatory agent. Pomalidomide is a ligand for CRBN. Cost-effective …

• Formula: C₁₃H₁₁N₃O₄
• Purity: 100% - 98.8%
• Color and Shape: Solid
• Molecular weight: 273.24

Pomalidomide

CAS: 19171-19-8

• Formula: C₁₃H₁₁N₃O₄
• Purity: ≥ 98.5%
• Color and Shape: Yellow to green powder
• Molecular weight: 273.24

Pomalidomide-d5

CAS: 19171-19-8

Applications Pomalidomide-d5 is the labeled analogue of Pomalidomide (P688200), a thalidomide derivative, a potent inhibitor …

• Formula: C₁₃D₅H₆N₃O₄
• Color and Shape: Neat
• Molecular weight: 278.27

Pomalidomide

CAS: 19171-19-8

Applications Pomalidomide is a thalidomide derivative, a potent inhibitor of TNF-α production. It is an …

• Formula: C₁₃H₁₁N₃O₄
• Color and Shape: Yellow
• Molecular weight: 273.24

Pomalidomide - Bio-X ™

CAS: 19171-19-8

Pomalidomide is an immunomodulatory agent that inhibits transcriptional regulation by interacting with the pomalidomide-binding protein, …

• Formula: C₁₃H₁₁N₃O₄
• Purity: Min. 99 Area-%
• Color and Shape: Powder
• Molecular weight: 273.24 g/mol

Pomalidomide

CAS: 19171-19-8

Pomalidomide is an immunomodulatory agent that inhibits transcriptional regulation by interacting with the pomalidomide-binding protein, …

• Formula: C₁₃H₁₁N₃O₄
• Purity: Min. 98 Area-%
• Color and Shape: Yellow Powder
• Molecular weight: 273.24 g/mol

Pomalidomide-d2 (Major)

CAS: 19171-19-8

• Formula: C₁₃D₂H₉N₃O₄
• Color and Shape: Neat
• Molecular weight: 275.26