CAS 191732-72-6

Lenalidomide

Description:

Lenalidomide is a synthetic derivative of thalidomide and is classified as an immunomodulatory drug. It is primarily used in the treatment of multiple myeloma and certain types of myelodysplastic syndromes. The chemical formula of lenalidomide is C13H13N3O3, and it features a unique structure that includes a phthalimide moiety, which contributes to its biological activity. Lenalidomide exhibits anti-inflammatory, anti-angiogenic, and anti-tumor properties, largely through modulation of the immune system and inhibition of pro-inflammatory cytokines. It is known to enhance T-cell and natural killer cell activity, promoting the body's ability to fight cancer. The drug is typically administered orally and has a relatively long half-life, allowing for convenient dosing schedules. Common side effects may include fatigue, nausea, and hematological abnormalities, necessitating regular monitoring of blood counts during treatment. Lenalidomide's mechanism of action and its efficacy in various hematological malignancies have made it a significant therapeutic agent in oncology.

Formula: C₁₃H₁₃N₃O₃

InChI: InChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)

InChI key: InChIKey=GOTYRUGSSMKFNF-UHFFFAOYSA-N

SMILES: O=C1N(CC=2C1=CC=CC2N)C3C(=O)NC(=O)CC3

Synonyms:

• 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione
• 2,6-Piperidinedione, 3-(4-amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-
• 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
• CC 5013
• Revimid

2,6-Piperidinedione, 3-(4-amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-

CAS: 191732-72-6

Formula: C₁₃H₁₃N₃O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 259.2606

Ref: IN-DA002FGA

Lenalidomide

CAS: 191732-72-6

Lenalidomide (CC-5013) is an orally immunomodulator. Lenalidomide is a ligand for the ubiquitin E3 ligase cereblon (CRBN). Cost-effective and quality-assured.

Formula: C₁₃H₁₃N₃O₃

Purity: 98% - 99.97%

Color and Shape: Yellow Solid

Molecular weight: 259.26

Ref: TM-T1642

Lenalidomide

CAS: 191732-72-6

Lenalidomide

Purity: ≥98%

Molecular weight: 259.26g/mol

Ref: 54-BUP17840

Lenalidomide

CAS: 191732-72-6

Lenalidomide

Purity: 98%

Molecular weight: 259.26g/mol

Ref: 54-OR1029170

Lenalidomide

CAS: 191732-72-6

Formula: C₁₃H₁₃N₃O₃

Purity: ≥ 98.0%

Color and Shape: White to off-white or beige powder

Molecular weight: 259.26

Ref: 7W-GP6222

Lenalidomide

CAS: 191732-72-6

Formula: C₁₃H₁₃N₃O₃

Color and Shape: Pale Yellow Solid

Molecular weight: 259.27

Ref: 4Z-L-261

Lenalidomide

CAS: 191732-72-6

Color and Shape: Neat

Ref: 86-MM3641.00

Lenalidomide-13C5-15N

CAS: 191732-72-6

Formula: C₈₁₃C₅H₁₃N₂₁₅NO₃

Molecular weight: 265.22

Ref: 4Z-L-2661

Lenalidomide

Controlled Product

CAS: 191732-72-6

Applications Lenalidomide is an immunomodulatory drug; analog of Thalidomide.
References Bartlett, J.B., et al.: Nature Rev., 4, 314 (2004), Mitsiades, C.S., et al.: Curr. Opin. Invest. Drugs, 5, 635 (2004), List, A., et al.: N. Engl. J. Med., 352, 549 (2005),

Formula: C₁₃H₁₃N₃O₃

Color and Shape: White

Molecular weight: 259.26

Ref: TR-L328000

Lenalidomide-d5

Controlled Product

CAS: 191732-72-6

Applications Lenalidomide-d5, is the labeled analogue of Lenalidomide (L328000), an immunomodulatory drug; analog of Thalidomide.
References Bartlett, J.B., et al.: Nature Rev., 4, 314 (2004), Mitsiades, C.S., et al.: Curr. Opin. Invest. Drugs, 5, 635 (2004), List, A., et al.: N. Engl. J. Med., 352, 549 (2005),

Formula: C₁₃H₈D₅N₃O₃

Color and Shape: Off-White

Molecular weight: 264.29

Ref: TR-L328003

Lenalidomide - Bio-X ™

Controlled Product

CAS: 191732-72-6

Lenalidomide is a thalidomide derivative that is used to treat multiple myeloma and anemia. This drug exerts immunomodulatory effects by altering cytokine production. Lenalidomide also directly inhibits the cullin ring E3 ubiquitin ligase complex.

Formula: C₁₃H₁₃N₃O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 259.26 g/mol

Ref: 3D-BL164614

Lenalidomide

Controlled Product

CAS: 191732-72-6

Inhibitor of E3 ubiquitin ligase cereblon; inducer of CK1α degradation

Formula: C₁₃H₁₃N₃O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 259.26 g/mol

Ref: 3D-FL24864

Lenalidomide

CAS: 191732-72-6

Formula: C₁₃H₁₃N₃O₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 259.265

Ref: 10-F078933

N-[3-Aminopropyl] Lenalidomide Trifluoroacetic Acid Salt

Controlled Product

CAS: 191732-72-6

Applications N-[3-Aminopropyl] Lenalidomide Trifluoroacetic Acid Salt is a derivative of Lenalidomide (L328000), an immunomodulatory drug; analog of Thalidomide.
References Bartlett, J.B., et al.: Nature Rev., 4, 314 (2004), Mitsiades, C.S., et al.: Curr. Opin. Invest. Drugs, 5, 635 (2004), List, A., et al.: N. Engl. J. Med., 352, 549 (2005),

Formula: C₁₆H₂₀N₄O₃·x(C₂HF₃O₂)

Color and Shape: Neat

Molecular weight: 316.36 + x(114.02)

Ref: TR-A609330