CAS 191732-72-6: Lenalidomide

Description: Lenalidomide is a synthetic derivative of thalidomide and is classified as an immunomodulatory drug. It is primarily used in the treatment of multiple myeloma and certain types of myelodysplastic syndromes. The chemical formula of lenalidomide is C13H13N3O3, and it features a unique structure that includes a phthalimide moiety, which contributes to its biological activity. Lenalidomide exhibits anti-inflammatory, anti-angiogenic, and anti-tumor properties, largely through modulation of the immune system and inhibition of pro-inflammatory cytokines. It is known to enhance T-cell and natural killer cell activity, promoting the body's ability to fight cancer. The drug is typically administered orally and has a relatively long half-life, allowing for convenient dosing schedules. Common side effects may include fatigue, nausea, and hematological abnormalities, necessitating regular monitoring of blood counts during treatment. Lenalidomide's mechanism of action and its efficacy in various hematological malignancies have made it a significant therapeutic agent in oncology.

Formula: C₁₃H₁₃N₃O₃

InChI: InChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)

InChI key: InChIKey=GOTYRUGSSMKFNF-UHFFFAOYSA-N

SMILES: O=C1NC(=O)C(N2C(=O)C=3C=CC=C(N)C3C2)CC1

Synonyms:

• 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione
• 2,6-Piperidinedione, 3-(4-amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-
• 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
• CC 5013
• Revimid

Lenalidomide

CAS: 191732-72-6

Lenalidomide (CC-5013) is an orally immunomodulator. Lenalidomide is a ligand for the ubiquitin E3 ligase …

• Formula: C₁₃H₁₃N₃O₃
• Purity: 98% - 99.97%
• Color and Shape: Yellow Solid
• Molecular weight: 259.26

2,6-Piperidinedione, 3-(4-amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-

CAS: 191732-72-6

• Formula: C₁₃H₁₃N₃O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 259.2606

Lenalidomide

CAS: 191732-72-6

• Formula: C₁₃H₁₃N₃O₃
• Purity: ≥ 98.0%
• Color and Shape: White to off-white or beige powder
• Molecular weight: 259.26

Lenalidomide

CAS: 191732-72-6

• Formula: C₁₃H₁₃N₃O₃
• Color and Shape: Pale Yellow Solid
• Molecular weight: 259.27

Lenalidomide

CAS: 191732-72-6

• Purity: 96.00%
• Color and Shape: Solid, Off-white powder
• Molecular weight: 259.2650146484375

Lenalidomide

CAS: 191732-72-6

• Formula: C₁₃H₁₃N₃O₃
• Color and Shape: Neat
• Molecular weight: 259.26

Lenalidomide, 98%

CAS: 191732-72-6

This Thermo Scientific brand product was originally part of the Acros Organics product portfolio. Some …

• Formula: C₁₃H₁₃N₃O₃
• Purity: 98%
• Color and Shape: White to light yellow to beige, Crystalline powder
• Molecular weight: 259.27

Lenalidomide-13C5-15N

CAS: 191732-72-6

• Formula: C₈₁₃C₅H₁₃N₂₁₅NO₃
• Molecular weight: 265.22

Lenalidomide

CAS: 191732-72-6

Applications Lenalidomide is an immunomodulatory drug; analog of Thalidomide. References Bartlett, J.B., et al.: Nature …

• Formula: C₁₃H₁₃N₃O₃
• Color and Shape: White
• Molecular weight: 259.26

Lenalidomide-d5

CAS: 191732-72-6

Applications Lenalidomide-d5, is the labeled analogue of Lenalidomide (L328000), an immunomodulatory drug; analog of Thalidomide. …

• Formula: C₁₃H₈D₅N₃O₃
• Color and Shape: Off-White
• Molecular weight: 264.29

Lenalidomide - Bio-X ™

CAS: 191732-72-6

Lenalidomide is a thalidomide derivative that is used to treat multiple myeloma and anemia. This …

• Formula: C₁₃H₁₃N₃O₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 259.26 g/mol

Lenalidomide

CAS: 191732-72-6

Inhibitor of E3 ubiquitin ligase cereblon; inducer of CK1α degradation

• Formula: C₁₃H₁₃N₃O₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 259.26 g/mol

N-[3-Aminopropyl] Lenalidomide Trifluoroacetic Acid Salt

CAS: 191732-72-6

Applications N-[3-Aminopropyl] Lenalidomide Trifluoroacetic Acid Salt is a derivative of Lenalidomide (L328000), an immunomodulatory drug; …

• Formula: C₁₆H₂₀N₄O₃·x(CHF₃O₂)
• Color and Shape: Neat
• Molecular weight: 316.36 + x(114.02)