CAS 192065-56-8

Benzenamine,4-(8-methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-, hydrochloride (1:1)

Description:

Benzenamine, 4-(8-methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-, hydrochloride (1:1), with CAS number 192065-56-8, is a chemical compound characterized by its complex structure that includes a benzene ring and a benzodiazepine moiety. This compound typically exhibits properties associated with both aromatic amines and benzodiazepines, which may include moderate solubility in polar solvents and potential biological activity. The presence of the hydrochloride indicates that it is a salt form, which often enhances solubility and stability in aqueous solutions. The dioxole and benzodiazepine components suggest potential pharmacological properties, possibly influencing central nervous system activity. As with many compounds in this class, it may be of interest in medicinal chemistry for its potential therapeutic applications. Safety and handling precautions should be observed, as compounds with amine and benzodiazepine structures can have specific toxicity profiles and regulatory considerations.

Formula: C₁₇H₁₅N₃O₂ClH

Synonyms:

• Benzenamine,4-(8-methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-, monohydrochloride(9CI)
• GYKI 52466 HCl
• GYKI 52466 Hydrochloride

4-(8-Methyl-9H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepin-5-yl)aniline hydrochloride

CAS: 192065-56-8

Formula: C₁₇H₁₆ClN₃O₂

Molecular weight: 329.7808

Ref: IN-DA002FMC

GYKI 52466 hydrochloride

CAS: 192065-56-8

Formula: C₁₇H₁₅N₃O₂·HCl

Molecular weight: 329.78

Ref: 7W-GK1164

Gyki 52466 hydrochloride

CAS: 192065-56-8

Gyki 52466 hydrochloride is an ATP-sensitive potassium channel inhibitor that prevents the opening of these channels in response to a depolarizing stimulus, thereby inhibiting the release of neurotransmitters. Gyki 52466 hydrochloride has been shown to inhibit neuronal uptake and increase extracellular glutamate concentrations in the brain. This drug has also been shown to affect locomotor activity and induce seizures in wild-type mice, while having no effect on knockout mice with no ion channel expression. Gyki 52466 hydrochloride has also been shown to be effective against cancer cells in vitro.

Formula: C₁₇H₁₆ClN₃O₂

Purity: Min. 95%

Molecular weight: 329.8 g/mol

Ref: 3D-SHA06556

GYKI 52466 HCl

CAS: 192065-56-8

GYKI 52466 is an AMPA antagonist with IC50 of 7.5 µM, also blocking kainate currents (IC50 11 µM) and reduces EPSCs and seizures in rats.

Formula: C₁₇H₁₆ClN₃O₂

Color and Shape: Solid

Molecular weight: 329.784

Ref: TM-T70063