CAS 19216-56-9: Prazosin

Description: Prazosin is a selective alpha-1 adrenergic antagonist primarily used in the treatment of hypertension and symptoms of benign prostatic hyperplasia. It works by blocking alpha-1 receptors on vascular smooth muscle, leading to vasodilation and a decrease in blood pressure. Prazosin is typically administered orally and has a relatively short half-life, necessitating multiple doses throughout the day for sustained effect. The compound is known for its ability to reduce peripheral resistance and improve urinary flow in patients with prostate enlargement. Additionally, it has been studied for its potential benefits in treating post-traumatic stress disorder (PTSD) due to its effects on reducing nightmares and improving sleep quality. Prazosin is generally well-tolerated, though it may cause side effects such as dizziness, headache, and orthostatic hypotension, particularly upon initiation of therapy. Its chemical structure includes a quinazoline ring, contributing to its pharmacological properties. As with any medication, it is essential for patients to consult healthcare professionals for appropriate dosing and monitoring.

Formula: C₁₉H₂₁N₅O₄

InChI: InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)

InChI key: InChIKey=IENZQIKPVFGBNW-UHFFFAOYSA-N

SMILES: O=C(C=1OC=CC1)N2CCN(C=3N=C(N)C=4C=C(OC)C(OC)=CC4N3)CC2

Synonyms:

• 2-[4-(2-Furoyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine
• 2-[4-(Furan-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine
• 4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazinyl 2-furyl ketone
• Furazosin
• Lentopres
• Methanone, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanyl-
• Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)-
• Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl)-
• Prazosina
• Prazosine
• [4-(4-Amino-6,7-Dimethoxyquinazolin-2-Yl)Piperazin-1-Yl](Furan-2-Yl)Methanone
• [4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanylmethanone
• Prazosin

(4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(furan-2-yl)methanone hydrochloride salt

CAS: 19216-56-9

• Purity: 95.0%
• Color and Shape: Solid
• Molecular weight: 383.408

Methanone, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanyl-

CAS: 19216-56-9

• Formula: C₁₉H₂₁N₅O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 383.4011

Prazosin Hydrochloride

CAS: 19216-56-919237-84-4

• Formula: C₁₉H₂₁N₅O₄·HCl
• Purity: >98.0%(T)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 419.87

Prazosin

CAS: 19216-56-9

Prazosin (Prazosine), an α1-blocker, acts as an inverse agonist at alpha-1 adrenergic receptors and is …

• Formula: C₁₉H₂₁N₅O₄
• Purity: 99.86%
• Color and Shape: White To Tan Powder Solid
• Molecular weight: 383.4

Prazosin

CAS: 19216-56-9

Applications Prazosin is a useful α1 and α2B-adrenoceptor antagonist.

• Formula: C₁₉H₂₁N₅O₄
• Color and Shape: Neat
• Molecular weight: 383.40

[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanyl-methanone

CAS: 19216-56-9

Leflunomide is a drug that belongs to the class of pyridones. It is used in …

• Formula: C₁₉H₂₁N₅O₄
• Purity: Min. 95%
• Molecular weight: 383.4 g/mol