CAS 192314-93-5

5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl]pyrimidine-2,4- diamine

Description:

5-[(2-Cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl]pyrimidine-2,4-diamine, with the CAS number 192314-93-5, is a synthetic organic compound characterized by its complex structure, which includes a pyrimidine ring and a chromenyl moiety. This compound features two amine groups at the 2 and 4 positions of the pyrimidine ring, contributing to its potential biological activity. The presence of the cyclopropyl group and methoxy substituents on the chromenyl part may influence its pharmacological properties, possibly enhancing its interaction with biological targets. The compound is likely to exhibit solubility in organic solvents, and its stability can be influenced by environmental factors such as pH and temperature. Due to its structural features, it may be of interest in medicinal chemistry, particularly in the development of therapeutic agents. However, specific biological activities, toxicity, and detailed physicochemical properties would require further investigation through experimental studies.

Formula: C₁₉H₂₂N₄O₃

InChI: InChI=1/C19H22N4O3/c1-24-15-8-11(7-12-9-22-19(21)23-18(12)20)13-5-6-14(10-3-4-10)26-16(13)17(15)25-2/h5-6,8-10,14H,3-4,7H2,1-2H3,(H4,20,21,22,23)

InChI key: InChIKey=HWJPWWYTGBZDEG-UHFFFAOYSA-N

SMILES: C(C1=C2C(=C(OC)C(OC)=C1)OC(C=C2)C3CC3)C=4C(N)=NC(N)=NC4

Synonyms:

• 2,4-Pyrimidinediamine, 5-[(2-cyclopropyl-7,8-dimethoxy-2H-1-benzopyran-5-yl)methyl]-
• 5-[(2-Cyclopropyl-7,8-dimethoxy-2H-1-benzopyran-5-yl)methyl]-2,4-pyrimidinediamine
• Ar 100
• Iclaprim
• 5-[(2-Cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl]pyrimidine-2,4-diamine
• 5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl]pyrimidine-2,4-diamine
• 5-((2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl)pyrimidine-2,4-diamine(WXG01982)
• Iclaprim Methanesulfonate
• diaMine
• 5-[(2-Cyclopropyl-7,8-diMethoxy-2H-1-benzopyran-5-yl)Methyl]-2,4-pyriMidine-
• 5-(2-Cyclopropyl-7,8-dimethoxy-2H-chromen-5-ylmethyl)-pyrimidine-2,4-diamine (ICLAPRIM]

5-[(2-Cyclopropyl-7,8-dimethoxy-2H-1-benzopyran-5-yl)methyl]-2,4-pyrimidinediamine

CAS: 192314-93-5

Formula: C₁₉H₂₂N₄O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 354.4030

Ref: IN-DA002FUB

Iclaprim

CAS: 192314-93-5

Iclaprim

Purity: ≥98%

Molecular weight: 354.4g/mol

Ref: 54-BUP04546

Iclaprim

CAS: 192314-93-5

Iclaprim (AR-100) is a novel specific bacterial Dihydrofolate inhibitor. It can inhibit the growth of S. aureus (MIC90: 0.06 μg/mL).

Formula: C₁₉H₂₂N₄O₃

Purity: 99.66%

Color and Shape: Solid

Molecular weight: 354.4

Ref: TM-TQ0113

Iclaprim

CAS: 192314-93-5

Formula: C₁₉H₂₂N₄O₃

Molecular weight: 354.41

Ref: 4Z-I-431

Iclaprim

Controlled Product

CAS: 192314-93-5

Applications Iclaprim is a novel antibacterial agent that is currently in development for the treatment of complicated skin and skin structure infections (cSSSI). Antibiotics.
References Cosgrove, S., et al.: Clin. Infect. Dis., 39, 539 (2004), Hawser, S., et al.: Biochem. Pharmacol., 71, 941 (2006), Laue, H., et al.: J. Antimicrob. Chemother., 60, 1391 (2007),

Formula: C₁₉H₂₂N₄O₃

Color and Shape: Neat

Molecular weight: 354.403

Ref: TR-I164000

Iclaprim

CAS: 192314-93-5

Iclaprim is an antibiotic, which is a synthetic diaminopyrimidine antimicrobial agent with a specific mechanism of action. It works by selectively inhibiting bacterial dihydrofolate reductase, a crucial enzyme in the bacterial folate synthesis pathway. This inhibition prevents the production of tetrahydrofolate, ultimately disrupting DNA, RNA, and protein synthesis in susceptible bacterial cells.

Formula: C₁₉H₂₂N₄O₃

Purity: Min. 95%

Molecular weight: 354.4 g/mol

Ref: 3D-FI24533