CAS 19237-53-7

Benzoyl glucuronide

Description:

Benzoyl glucuronide is a chemical compound that serves as a metabolite of benzoyl peroxide, commonly used in acne treatment. It is characterized by its glucuronide structure, which involves the conjugation of benzoyl with glucuronic acid, a sugar acid that plays a significant role in the detoxification and excretion of various substances in the body. This compound is typically found in biological fluids, such as urine, following the metabolism of benzoyl peroxide. Benzoyl glucuronide is generally soluble in water due to its polar glucuronic acid component, which enhances its excretion through renal pathways. Its presence in biological samples can be indicative of benzoyl peroxide exposure and is often analyzed in pharmacokinetic studies. The compound is not known to exhibit significant toxicity, making it a relatively safe metabolite in the context of its parent compound's therapeutic use. Overall, benzoyl glucuronide is an important marker in understanding the metabolic pathways of certain dermatological treatments.

Formula: C₁₃H₁₄O₈

InChI: InChI=1/C13H14O8/c14-7-8(15)10(11(17)18)20-13(9(7)16)21-12(19)6-4-2-1-3-5-6/h1-5,7-10,13-16H,(H,17,18)/t7-,8-,9+,10-,13-/m0/s1

InChI key: InChIKey=NLOPFVNXNMEEDI-UNLLLRGISA-N

SMILES: O(C(=O)C1=CC=CC=C1)[C@@H]2O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]2O

Synonyms:

• 1-O-benzoyl-beta-D-glucopyranuronic acid
• Benzoic acid glucuronide
• Benzoic acid β-<span class="text-smallcaps">D</span>-glucuronide
• Benzoyl-β-<span class="text-smallcaps">D</span>-glucuronide
• Glucopyranuronic acid, 1-benzoate
• Glucopyranuronic acid, 1-benzoate, β-<span class="text-smallcaps">D</span>-
• Glucosiduronic acid, 1-benzoate
• beta-D-Glucopyranuronic acid, 1-benzoate
• β-<span class="text-smallcaps">D</span>-Glucopyranuronic acid, 1-benzoate
• Benzoyl glucuronide
• Benzoic acid β-D-glucuronide
• β-D-Glucopyranuronic acid, 1-benzoate
• Glucopyranuronic acid, 1-benzoate, β-D-
• Benzoic acid acyl-β-D-glucuronide
• Benzoic acid-acyl-b-D-glucuronide
• Benzoic acid-acyl-beta-D-glucuronide min. 98%
• Benzoic acid-acyl-Beta-D-glucuronide
• Benzoic Acid Acyl-β-D-glucuronide
• Benzoic Acid Acyl-2-D-glucuronide

Benzoic acid-acyl-β-D-glucuronide

CAS: 19237-53-7

Benzoic acid-acyl-β-D-glucuronide

Purity: >98%

Molecular weight: 298.24546g/mol

Ref: 54-BICL4036

Benzoic acid acyl-β-D-glucuronide

CAS: 19237-53-7

Ref: 7W-GC8363

Benzoic Acid Glucuronide

CAS: 19237-53-7

Formula: C₁₃H₁₄O₈

Molecular weight: 298.25

Ref: 4Z-B-085004

Benzoic Acid Acyl-b-D-glucuronide

Controlled Product

CAS: 19237-53-7

Stability Hygroscopic
Applications Benzoic Acid Acyl-β-D-glucuronide is in the class of 1-β-D-Acyl glucuronides (βGAs) which are potentially highly reactive metabolites which are capable of binding to protein molecules and resulting in adverse drug reactions observed in medications.
References Baba, A. et al.: Chem. Res. Toxicol., 22, 158 (2009); McMahon, T. et al.: Drug. Metab. Disp., 17, 506 (1989)

Formula: C₁₃H₁₄O₈

Color and Shape: Neat

Molecular weight: 298.2455

Ref: TR-B203930

Benzoic acid-acyl-b-D-glucuronide

CAS: 19237-53-7

Benzoic acid-acyl-b-D-glucuronide is a β-glucuronide linker that is cleaved by β-glucuronidase enzymes. This allows controlled release of the payload to the targeted cells.

Formula: C₁₃H₁₄O₈

Purity: Min. 95%

Molecular weight: 298.25 g/mol

Ref: 3D-MB44738

Benzoyl Glucuronide

CAS: 19237-53-7

Formula: C₁₃H₁₄O₈

Molecular weight: 298.25

Ref: ST-EA-CP-B9012